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https://www.ncbi.nlm.nih.gov/pubmed/18532925
Mannose-targeted systems for the delivery of therapeutics. Irache JM(1), Salman HH, Gamazo C, Espuelas S. Author information: (1)University of Navarra, Department of Pharmaceutics and Pharmaceutical Technology, Apartado 177, 31008 Pamplona, Spain. [email protected]: Juan M Irache, Hesham H Salman, Carlos Gamazo, Socorro Espuelas
https://www.researchgate.net/profile/Juan_Irache/publication/5324604_Mannose-targeted_systems_for_the_delivery_of_therapeutics/links/0912f50a2769fd2b81000000.pdf
1 Mannose-targeted systems for the delivery of therapeutics Juan M. Irache1,*, Hesham H. Salman1, Carlos Gamazo2, Socorro Espuelas1 Department of Pharmaceutics and Pharmaceutical Technology1 ...
https://www.researchgate.net/publication/5324604_Mannose-targeted_systems_for_the_delivery_of_therapeutics
Mannose-targeted systems for the delivery of therapeutics Juan M. Irache1,*, Hesham H. Salman1, Carlos Gamazo2, Socorro Espuelas1 Department of Pharmaceutics and Pharmac eutical Technology 1 ...
https://www.tandfonline.com/doi/abs/10.1517/17425247.5.6.703
Feb 12, 2018 · Background: The specific targeting of nanomedicines to mannose receptors, highly expressed in cells of the immune system, performs a useful strategy for improving the efficacy of vaccines and chemotherapy.Objective: This review discusses the potential of mannose-targeted drug/antigen delivery systems for vaccination and treatment of diseases localized in macrophages …Author: Juan M Irache, Hesham H Salman, Carlos Gamazo, Socorro Espuelas
https://www.academia.edu/7701365/Mannose-targeted_systems_for_the_delivery_of_therapeutics
Mannose-targeted systems for the delivery of therapeutics
https://onlinelibrary.wiley.com/doi/abs/10.1002/adhm.201701398
In this work, the potential of mannose‐ and mannose‐6‐phosphate‐targeted delivery systems in cancer therapy is discussed, emphasizing their broad application both in direct treatments against cancer cells with conventional chemotherapeutics or by gene therapy and also their encouraging capabilities in immunotherapy and diagnostics purposes.Author: Elena Dalle Vedove, Gabriella Costabile, Olivia M. Merkel
https://www.sciencedirect.com/science/article/pii/S1549963417301132
Nevertheless, nonspecific off-target delivery is a major hurdle for siRNA therapeutics. Development of appropriate delivery systems to efficiently deliver siRNA to tumor sites is highly important. In this study, we have successfully prepared a Man-SiO 2 @LDH nanocomposite by grafting mannose onto the SiO 2-coated LDH nanocomposite. The presence ...Author: Li Li, Run Zhang, Wenyi Gu, Zhi Ping Xu
https://www.hindawi.com/journals/jir/2015/680620/
Along this developmental trajectory, DC-targeted nanoparticle gene delivery systems may be an imminent next step forward for nonviral tumor vaccine delivery. In this brief report, established conjugation strategies for both polymeric and liposomal gene delivery systems will be described.Author: Kyle K. L. Phua
https://www.hindawi.com/journals/jdd/2011/727241/
Journal of Drug Delivery + Journal Menu. PDF. Table of Contents ... by tumoricidal activation of tissue macrophages using liposome-encapsulated immunomodulators,” Pharmacology and Therapeutics, vol. 78, no. 3 ... H. H. Salman, C. Gamazo, and S. Espuelas, “Mannose-targeted systems for the delivery of therapeutics,” Expert Opinion on Drug ...Author: Ciara Kelly, Caroline Jefferies, Sally-Ann Cryan
https://www.sciencedirect.com/science/article/pii/S1367593109000465
The vitamin, folic acid, is required in one carbon metabolic reactions, and consequently, is essential for the synthesis of nucleotide bases. Uptake of folates into virtually all cells of the body is mediated by either the reduced folate carrier [13, 14] or the proton coupled folate transporter [].Because neither of these membrane-spanning transport proteins displays affinity for folate ...Author: Philip Stewart Low, Sumith Anurasiri Kularatne
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