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https://www.nature.com/articles/3302720
Feb 07, 2006 · Magnetic nanoparticle-based transfection methods are based on the principles developed in the late 1970s by Widder and others for magnetically targeted drug delivery.Author: J Dobson
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4046008/
May 21, 2014 · Polymer-based nanoparticles. Cationic polymers are one of the most significant non-viral gene delivery systems. These polymers have positively charged groups in their backbone and can interact with the negative charge of anionic genetic materials [].Cationic polymers can bind to DNA molecules to form neutralized, nanometer-sized complexes known as polyplexes.Author: Solmaz Maleki Dizaj, Samira Jafari, Ahmad Yari Khosroushahi
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527670/
Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.Author: Stuart McBain, Humphrey Hak Ping Yiu, Jon Dobson
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0102886
A Magnetic Nanoparticle-Based Multiple-Gene Delivery System for Transfection of Porcine Kidney Cells Yan Wang, Affiliation Institute of Environment and Sustainable Development in Agriculture, Chinese Academy of Agricultural Sciences, Zhongguancun Haidian District, Beijing, ChinaAuthor: Yan Wang, Haixin Cui, Kui Li, Changjiao Sun, Wei Du, Jinhui Cui, Xiang Zhao, Wenjie Chen
https://www.nature.com/articles/3302720
Feb 07, 2006 · Magnetic nanoparticle-based transfection methods are based on the principles developed in the late 1970s by Widder and others for magnetically targeted drug delivery.Author: J Dobson
https://www.researchgate.net/publication/7311203_Gene_therapy_progress_and_prospects_Magnetic_nanoparticle-based_gene_delivery
that magnetic nanoparticle-based drug/gene delivery is likely to be most effective for target sites near the surface of the body , close to the source of the magnetic field.
https://www.intechopen.com/books/advanced-technology-for-delivering-therapeutics/medicated-nanoparticle-for-gene-delivery
Magnetofection is a methodology based on the association of magnetic nanoparticle with gene vectors in order to optimize/enhance gene delivery in the presence of a magnetic field. The magnetic field is applied to move the MNP-gene vector complexes toward the target site.Author: Sakthivel Lakshmana Prabu, Timmadonu Narasimman KuppusamiSuriyaprakash, Rathinasabapathy Thirumuruga...
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