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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276294/
May 20, 2020 · HOHA lactone upregulates caspase 3/7 in ARPE-19 cells. The microscopy imaging of caspase activation in ARPE-19 cells using the NucView 488 caspase-3 assay kit. ARPE-19 cells were challenged with 15 μM HOHA lactone in DMEM/F12 medium for 18 hours. Cells were then stained using 5 μM DEVD-NucView 488-substrate to detect the activation of caspase ...Cited by: 2
https://pubmed.ncbi.nlm.nih.gov/20399994/
Plasma concentrations of rosuvastatin, N-desmethyl rosuvastatin, and rosuvastatin lactone were measured through 72 hours after administration of single doses and through 96 hours after administration of multiple doses. Blood samples were obtained within 30 minutes before dosing on days 7, 8, and 9 for the assessment of pharmacokinetic ...Cited by: 13
https://pubchem.ncbi.nlm.nih.gov/compound/Descarbamoylcefuroxime-lactone
Descarbamoylcefuroxime lactone C15H13N3O6S CID 71587890 - structure, chemical names, physical and chemical properties, classification, patents, literature ...
https://pubmed.ncbi.nlm.nih.gov/8853931/
Topotecan lactone is widely distributed into the peripheral space, with a mean volume of distribution (Vd) at steady-state of 75 L/m2. The mean total body clearance of the lactone form is 30 L/h/m2, with a mean elimination half-life (t1/2 beta) of 3 hours; renal clearance accounts for approximately 40% of the administered dose with a large ...Cited by: 232
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