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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3276033/
Pulmonary delivery of drug has become an attractive target and of tremendous scientific and biomedical interest in the health care research area as the lung is capable of absorbing pharmaceuticals either for local deposition or for systemic delivery.
http://www.pharmtech.com/four-challenges-pulmonary-drug-delivery
Sep 01, 2017 · Pulmonary drug delivery is receiving increased attention as a non-invasive means for local treatment of a wide range of major lung diseases; this route of administration, however, poses additional challenges for medicinal and formulation chemists.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/pulmonary-drug-delivery
7.6 Conclusion. Pulmonary drug delivery is getting more and more magnitude. This is on account of the specific physiological environment of the lung as an absorption and treatment organ. The development of inhalable insulin can be perceived as a milestone in pulmonary drug delivery.
https://erj.ersjournals.com/content/erj/44/3/765.full.pdf
The lung is a unique organ for drug delivery. Its large surface area, thin epithelium layer and rich blood supply ensure fast drug absorption. These properties offer not only the possibility to treat lung disease, but also allow for the systemic application of drugs.Author: Sabine H. van Rijt, Thomas Bein, Silke Meiners
https://www.pharmaexcipients.com/nanotechnology/multifunctional-nanocarriers-lung-drug-delivery/
The devised strategies are mainly directed at three distinct areas of lung drug delivery, encompassing the delivery of proteins and protein-based materials, either for local or systemic application, the delivery of antibiotics, and the delivery of anticancer drugs—the latter two comprising local delivery approaches.
https://www.atsjournals.org/doi/full/10.1513/pats.200409-049TA
Dec 01, 2004 · No noninvasive route of drug delivery provides the bioavailability of the pulmonary epithelium. The lungs are far more permeable to macromolecules than any other portal of entry into the body . Some of the most promising therapeutic agents are peptides and proteins, which could be inhaled instead of injected, thereby improving compliance.Author: John S. Patton, C. Simone Fishburn, Jeffry G. Weers
https://aerosol-soc.com/events/ddl2019/
The Drug Delivery to the Lungs (DDL) Conference provides an annual forum for scientists, academics, clinicians, regulatory and industry specialists involved in developing medicines for inhalation. DDL2019 will have five themed sessions each with a combination of invited and submitted lectures given by experts in the field of inhalation and students working to advance respiratory science. Alongside the lecture …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1884307/
Apr 19, 2002 · As the end organ for the treatment of local diseases or as the route of administration for systemic therapies, the lung is a very attractive target for drug delivery. It provides direct access to disease in the treatment of respiratory diseases, while providing an enormous surface area and a relatively low enzymatic, controlled environment for systemic absorption of medications.Author: N. R. Labiris, M. B. Dolovich
https://www.nibib.nih.gov/science-education/science-topics/drug-delivery-systems-getting-drugs-their-targets-controlled-manner
In drug delivery research, this means starting with a delivery method. The target may be whole organs (heart, lung, brain), tissue types (muscle, nerve), disease-specific …
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