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https://www.researchgate.net/publication/26816636_GENIE_catheter_for_liquid_local_drug_delivery
In conclusion the GENIE™ catheter for liquid local drug deliver y is an easy to use technique which can serve as an alternative for stent based local drug delivery .
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3861011/
This local drug delivery catheter system is described as OCI (Occlusion, Containment, Infusion) therapeutics allowing site specific, localized drug delivery across any coronary lesion. The potential disadvantage of traditional method (passing through guide catheter) is >50% of the drug will be washed away in systemic circulation and other 20 ...Author: G. Sengottuvelu, V. Ravi Sekar
https://patents.google.com/patent/US6689099B2/en
A catheter for injecting medication to a specific point within a patient comprises a drug delivery lumen extending from a proximal end of the catheter to an injection port. The catheter comprises a mechanism for angularly pushing the injection port outwardly away from the body of the catheter into an artery wall so that medication can be injected directly into the artery wall.Author: Daryush Mirzaee
https://www.cathlabdigest.com/articles/The-ClearWay%E2%84%A2-RX-Local-Therapeutic-Infusion-Catheter
Apr 29, 2010 · ClearWay (Atrium Medical, Hudson, NH) is a low-profile, rapid-exchange therapeutic infusion catheter and is indicated for localized perfusion of various diagnostic and therapeutic agents into the coronary and peripheral vasculature. The ClearWay therapeutic infusion catheter enables local drug delivery to reach approximately a 500-fold greater drug concentration versus systemic delivery.
https://www.sciencedirect.com/science/article/pii/106214589500056P
KNOWLEDGE BASE BRIEF REVIEW Catheter-Based Local Drug Delivery Robert L Wilensky, MD and I(eith L March, MD, PhD, Krannert Institute of Cardiology, Indiana University Medical Center, Indianapolis, Indiana ~ he localized nature of restenosis has made the local application of highly concentrated pharmacologic agents or genetic material an attractive therapeutic option.Author: Robert L. Wilensky, Keith L. March
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3635112/
The efficacy of local drug delivery has been demonstrated in the coronary circulation with the current clinical use of drug-eluting stents (DES). Until recently, however, DES were not found to be efficacious in the peripheral circulation.Author: Stephen M. Seedial, Stephen M. Seedial, Soumojit Ghosh, R. Scott Saunders, Pasithorn A. Suwanabol, X...
https://academic.oup.com/bjaed/article/14/1/27/336442
Sep 04, 2013 · Intrathecal drug delivery (ITDD) systems comprise an IT catheter connected to a drug reservoir, which may be externalized and connected to a pump, or fully implanted. Two groups of patients may benefit from ITDD: those with spasticity (baclofen) and those with refractory pain.Author: Louise Lynch
https://patents.google.com/patent/US6283947B1/en
A catheter for injecting medication to a specific point within a patient comprises a drug delivery lumen extending from a proximal end of the catheter to an injection port. The catheter comprises a mechanism for angularly pushing the injection port outwardly away from the body of the catheter into an artery wall so that medication can be injected directly into the artery wall.Author: Daryush Mirzaee
https://academic.oup.com/cardiovascres/article/35/3/405/374433
Sep 01, 1997 · 3.1 Balloon catheter delivery systems 3.1.1 Double balloon (Fig. 2a) The earliest approach to percutaneous local drug delivery involved the use of a double balloon catheter . This device is passed over a guidewire like a conventional angioplasty balloon, the dual balloons are inflated proximal and distal to the site of injury, and drug is ...Author: David Brieger, Eric Topol
https://www.sciencedirect.com/science/article/pii/S0142961299002811
However, low drug concentrations have been obtained and possible additional arterial injury may incur when these modes of delivery have been utilized . The present study was conducted to develop a balloon catheter loaded with high drug content and to determine its efficacy of local drug delivery without further damage to the vessel wall. 2.Author: T Richey, H Iwata, H Oowaki, E Uchida, S Matsuda, Y Ikada
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