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https://loveperio.com/2012/08/10/localized-delivery-antibiotics-in-periodontal-therapy/
Aug 10, 2012 · As a follow up to the post discussing the use of systemic antibiotics in the treatment of periodontal disease, I decided to discuss the use of localized delivery antibiotics and chemotherapeutics in periodontal therapy. Dispensing syringe and minocycline-loaded cartridges for delivery of local antibiotics (Arestin).
https://totaldentalcare.com/2018/04/16/local-delivery-antibiotics/
Local delivery antibiotics are antibiotic medications that are strategically placed in the periodontal pockets to deliver a specific dose of medication over a set period of time. There are various forms of local delivery antibiotics can come in, such as chips, fibers, polymers, and trays.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467876/
Sub-gingival scaling in combination with local delivery of antibiotics is a good way to manage isolated sites of recurring disease, while full mouth scaling and systemic antibiotics or host modulation therapy can be used to treat a generalized recurrence.Author: Abinaya Prakasam, S. Sugumari Elavarasu, Ravi Kumar Natarajan
https://www.clicktocurecancer.info/periodontal-disease/local-delivery-of-antibiotics.html
The limitations of niouthrinsing and irrigation have prompted research tor the development of alternative delivery systems. Recently, advances in delivery technology have resulted in the controlled release of drugs (Table 50-3). I he requirements for treating periodontal disease include a means for targeting an antimicrobial to infection sites and sustaining its localized concentration at ...
http://www.knoxperio.com/procedures/periodontal-disease-treatments/locally-delivered-antibiotics/
Local delivery antimicrobials are medications that are delivered directly into periodontal pockets to suppress or eradicate periodontal bacteria. Local delivery antimicrobials may contain an antibiotic agent such as tetracycline, minocycline or metronidazole that’s released into the pocket over time.
https://mysandiegodentalimplant.com/antibiotics/locally-delivered-antibiotics/
The advantages of using locally delivered antibiotics include the delivery of a high concentration of antibiotics to a localized area without systemic involvement, prolonged release over time, minimal risk of developing bacterial resistance, elimination of gastrointestinal or other adverse effects related to the use of systemic antibiotics as well as reduced risk of noncompliance with systemic antibiotic regimens.
https://www.researchgate.net/publication/327499589_Local_drug_delivery_in_periodontal_diseases-_A_review
Conclusions: In patients with type 2 DM and CP, local delivery of 1% ALN into periodontal pockets resulted in a significant increase in the PD reduction, CAL gain, and improved bone fill compared ...
https://www.ncbi.nlm.nih.gov/pubmed/11709978/
Local delivery of antibacterial agents into periodontal pockets has been extensively developed and investigated since the late 1970s and many systems have been designed to maintain high levels of antimicrobial agents in the crevicular fluid with minimal systemic uptake.Author: Kinane Df
https://www.ihealthcareanalyst.com/report/periodontal-disease-therapeutics-market/
Scaling and root planing is sometimes followed by adjunctive therapy such as local delivery antimicrobials, systemic antibiotics, and host modulation, as needed on a case-by-case basis. Dentists and microbiologists across the globe have embraced the usage of antibiotics as an adjunctive therapy for management of periodontal diseases.4.5/5(4)
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