Liposomes Promote Pulmonary Glucocorticoid Delivery

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Liposome-encapsulated dexamethasone attenuates ventilator ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3130950/
    Systemic glucocorticoid therapy may effectively attenuate lung inflammation but also induce severe side-effects. Delivery of glucocorticoids by liposomes could therefore be beneficial. We investigated if liposome-encapsulated dexamethasone inhibited ventilator-induced lung inflammation.Author: M. A. Hegeman, P. M. Cobelens, Jaam Kamps, M. P. Hennus, N. J.G. Jansen, M. J. Schultz, A. J. Van Vu...

Pulmonary delivery of liposomes - ScienceDirect

    https://www.sciencedirect.com/science/article/pii/016836599390180D
    An overview of current data on pulmonary delivery of liposomes is provided, entailing fate of aerosols in the respiratory tract, physicochemical characterization of liposome aerosols, their therapeutic applications, pulmonary fate and kinetics, and pulmonary safety.Author: Hans Schreier, Ricardo J. Gonzalez-Rothi, Arlene A. Stecenko

Liposome‐encapsulated dexamethasone attenuates ventilator ...

    https://bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/j.1476-5381.2011.01314.x
    BACKGROUND AND PURPOSE Systemic glucocorticoid therapy may effectively attenuate lung inflammation but also induce severe side‐effects. Delivery of glucocorticoids by liposomes could therefore be beneficial. We investigated if liposome‐encapsulated dexamethasone inhibited ventilator‐induced lung …Author: M. A. Hegeman, P. M. Cobelens, Jaam Kamps, M. P. Hennus, N. J.G. Jansen, M. J. Schultz, A. J. Van Vu...

Liposome Delivery Systems for Inhalation: A Critical ...

    https://www.ncbi.nlm.nih.gov/pubmed/26938856/
    Liposomes can entrap anticancer drugs and localise their action in the lung following pulmonary delivery. The safety of inhaled liposomes incorporating anticancer drugs depends on the anticancer agent used and the amount of drug delivered to the target cancer in the lung.Author: Mindaugas Rudokas, Mohammad Najlah, Mohamed Albed Alhnan, Abdelbary Elhissi

Glucocorticoid-loaded liposomes induce a pro-resolution ...

    https://www.sciencedirect.com/science/article/pii/S014296121830245X
    Glucocorticoid-loaded liposomes induce a pro-resolution phenotype in human primary macrophages to support chronic wound healing ... in particular upon shell modification with phosphatidylserine, promote dexamethasone delivery to macrophages and induce a phenotype suitable to support chronic wound healing. ... Quantification of the engulfment of ...Author: Anne Gauthier, Anne Gauthier, Andreas Fisch, Klaus Seuwen, Birgit Baumgarten, Heinz Ruffner, Alexand...

Pulmonary Delivery of Liposome-Encapsulated Drugs in ...

    https://link.springer.com/article/10.1007/BF03259296
    Nov 03, 2012 · Microencapsulation of a number of drugs in microscopic phospholipid vesicles (liposomes) for site-targeted delivery of compounds is a novel area of drug delivery. More novel is the application of this concept for aerosol delivery of drugs to the lungs, particularly as it applies to the development of topical therapies for asthma. Although still in its relative infancy, pulmonary drug …Author: Ricardo J. Gonzalez-Rothi, Hans Schreier

(PDF) Composition Influence on Pulmonary Delivery of ...

    https://www.researchgate.net/publication/259153588_Composition_Influence_on_Pulmonary_Delivery_of_Rifampicin_Liposomes
    Composition Influence on Pulmonary Delivery of Rifampicin Liposomes Article (PDF Available) in Pharmaceutics 4(4):590-606 · December 2012 with 109 Reads How we measure 'reads'

Liposomes for Pulmonary Drug Delivery SpringerLink

    https://link.springer.com/chapter/10.1007/978-1-4419-9745-6_14
    May 25, 2011 · Abstract. Liposomes have been widely used in pulmonary drug delivery for ­multiple applications including solubilization, sustained release, cellular and intracellular ­targeting, minimization of toxicity, and facilitation of absorption.Author: Janani Swaminathan, Carsten Ehrhardt

Liposomes As Drug Delivery Systems for the Treatment of TB

    https://www.medscape.com/viewarticle/752329_4
    Nov 05, 2019 · Liposome nanocarriers are promising new delivery systems for anti-TB drugs by both intravenous and inhaled routes. ... Liposome-based Drug Delivery Therapy ...

Targeted delivery of liposomal dexamethasone phosphate to ...

    https://www.researchgate.net/publication/38086428_Targeted_delivery_of_liposomal_dexamethasone_phosphate_to_the_spleen_provides_a_persistent_therapeutic_effect_in_rat_antigen-induced_arthritis
    Targeted delivery of liposomal dexamethasone phosphate to the spleen provides a persistent therapeutic effect in rat antigen-induced arthritis ... Liposomes Promote Pulmonary Glucocorticoid ...

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