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https://www.ncbi.nlm.nih.gov/pubmed/18479776
Jun 30, 2008 · Echogenic liposomes have been produced by different preparation methods, including lyophilization, pressurization, and biotin-avidin binding. Presently, significant in vivo applications of liposomal ultrasound-based drug and gene delivery are being made in cardiac disease, stroke and tumor therapy.Author: Shao-Ling Huang
https://www.sciencedirect.com/science/article/pii/S0169409X08000823
Jun 30, 2008 · Echogenic liposomes have been produced by different preparation methods, including lyophilization, pressurization, and biotin–avidin binding. Presently, significant in vivo applications of liposomal ultrasound-based drug and gene delivery are being made in cardiac disease, stroke and tumor therapy. Translation of these vehicles into the clinic will require a better understanding of …Author: Shao-Ling Huang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1361256/
Delivery of genetic material is greatly enhanced by ultrasound in the presence of microbubbles. Attaching the DNA directly to the microbubbles or to gas-containing liposomes enhances gene uptake even further. US-enhanced gene delivery has been studied in various tissues including cardiac, vascular, skeletal muscle, tumor and even fetal tissue.Author: William G. Pitt, Ghaleb A. Husseini, Bryant J. Staples
https://www.researchgate.net/publication/5371302_Liposomes_in_ultrasonic_drug_and_gene_delivery
Liposome-based drug and gene delivery systems have potential for significant roles in a variety of therapeutic applications. Recently, liposomes have been used to entrap gas and drugs for ultrasound-controlled drug release and ultrasound-enhanced drug delivery.
https://www.sciencedirect.com/science/article/pii/S0168365913000266
Apr 10, 2013 · Ultrasonic cavitation perturbs the cell membrane, making transient pores in the membrane that facilitates drug and gene delivery . Microbubbles in the form of ultrasound contrast agents can enhance the efficacy of gene and drug delivery without damaging the cells [24] .Author: Marjan Javadi, William G. Pitt, Christopher M. Tracy, Jeffery R. Barrow, Barry M. Willardson, Jonath...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Most liposomal formulations used for gene delivery consist of a combination of charged lipids and neutral helper lipids [ 12, 22 – 24, 26, 28 ]. The neutral helper lipids used are often dioleoylphosphatidylethanolamine (DOPE), which is the most widely used neutral helper lipid, or dioleoylphosphatidylcholine (DOPC).Author: Daniel A. Balazs, Wt. Godbey
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2490710/
Jun 30, 2008 · The review of liposomes for ultrasonic drug and gene delivery is found elsewhere in this journal issue . Solid lipid nanoparticles consist of a solid lipid core that can carry a hydrophobic drug, which is often stabilized by an external monolayer of steric or charged surfactant.Author: Ghaleb A. Husseini, William G. Pitt
https://aasldpubs.onlinelibrary.wiley.com/doi/full/10.1002/hep.510270319
To improve liposome‐directed therapy of liver disease and gene delivery, it would be beneficial to selectively target hepatocytes. For this purpose, conventional liposomes (CL) were labeled with asia...Author: Jian Wu, Pei Liu, Jian Liang Zhu, Sivaramaiah Maddukuri, Mark A Zern
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