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https://www.ncbi.nlm.nih.gov/pubmed/18976130
BACKGROUND: Targeted delivery of antithrombotic (thrombolytic) drugs is expected to increase their efficacy and decrease side effects, especially in the case of thrombolytic enzymes. Liposomes, phospholipid nanosized bubbles with a bilayered membrane structure, have drawn a lot of interest as pharmaceutical carriers for drugs and genes.Author: Tamer A Elbayoumi, Vladimir P Torchilin
https://www.tandfonline.com/doi/abs/10.1517/17425240802497457
Background: Targeted delivery of antithrombotic (thrombolytic) drugs is expected to increase their efficacy and decrease side effects, especially in the case of thrombolytic enzymes. Liposomes, phospholipid nanosized bubbles with a bilayered membrane structure, have drawn a lot of interest as pharmaceutical carriers for drugs and genes.Author: Tamer A Elbayoumi, Vladimir P Torchilin
https://www.researchgate.net/publication/23443681_Liposomes_for_targeted_delivery_of_antithrombotic_drugs
Targeted delivery of antithrombotic (thrombolytic) drugs is expected to increase their efficacy and decrease side effects, especially in the case of thrombolytic enzymes. Liposomes, phospholipid...
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Advantages of liposomes as a drug delivery system for antimicrobials are: • Improvement and control over pharmacokinetics and pharmacodynamics. • Decreased toxicity. • Enhanced drug activity against intracellular pathogens. • Liposomes used as target selective. • Enhanced activity against ...Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946534/
Nov 04, 2013 · Herein we describe an antithrombotic agent formed through the conjugation of direct thrombin inhibitors to the surface of unilamellar liposomes. The use of a direct thrombin inhibitor conjugated to the surface of the liposome would allow for high affinity and avidity binding and targeting to thrombin at the site of acute thrombosis.Author: Rohun U. Palekar, Jacob W. Myerson, Paul H. Schlesinger, J. Evan Sadler, Hua Pan, Samuel A. Wickline
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Vikas Kumar, in Nanotechnology-Based Approaches for Targeting and Delivery of Drugs and Genes, 2017 Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Ligand-targeted liposomes offer a vast potential for site-specific delivery of drugs to designated cell types or organs in vivo, which selectively express or over-express specific ligands (e.g., receptors or cell adhesion molecules) at the site of disease (Willis and Forssen, 1998; Hua, 2013 ).Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2939703/
The use of PEGylated liposomes in the development of drug delivery applications for the treatment of hemophilia. Rivka Yatuv ... Instead of encapsulating the drug, PEGylated liposomes are used as carriers with the protein bound non-covalently ... Torchilin VP. Liposomes for targeted delivery of antithrombotic drugs. Expert Opin Drug Deliv. 2008 ...Author: Rivka Yatuv, Micah Robinson, Inbal Dayan-Tarshish, Moshe Baru
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Within a few years, a variety of enclosed phospholipid bilayer structures consisting of single bilayers, initially termed ‘bangosomes’ and then ‘liposomes’ , were described , and the early pioneers such as Gregory Gregoriadis, established the concept that liposomes could entrap drugs and be used as drug delivery systems , , , .Author: Theresa M. Allen, Pieter R. Cullis
https://en.wikipedia.org/wiki/Liposome
A liposome is a spherical vesicle having at least one lipid bilayer. The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Liposomes can be prepared by disrupting biological membranes. Liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg phosphatidylethanolamine, so long as they are compatible with lipid bilayer structure. A liposome …
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