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https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Jan A.A.M. Kamps, Gerrit L. Scherphof, in Methods in Enzymology, 2004. Introduction. In the development of liposomal drug delivery systems, pharmacokinetics, biodistribution, and cellular uptake of such systems are major issues to be dealt with. Depending on the aim of a particular study, a variety of experimental setups and methods are available to determine the in vivo behavior of liposomes ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · Types of liposomal drug delivery platforms. In general, there are four key types of liposomal delivery systems—conventional liposomes, sterically-stabilized liposomes, ligand-targeted liposomes, and a combination of the above (Figure (Figure1). 1).Conventional liposomes were the first generation of liposomes to be developed.Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
The first closed bilayer phospholipid systems, called liposomes, were described in 1965 and soon were proposed as drug delivery systems. The pioneering work of countless liposome researchers over almost 5 decades led to the development of important technical advances such as remote drug loading, extrusion for homogeneous size, long-circulating (PEGylated) liposomes, triggered release liposomes ...Author: Theresa M. Allen, Pieter R. Cullis
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Liposomes as a drug delivery system include benefits like improved pharmacokinetics and pharmacodynamics, decreased toxicity, enhanced therapeutic efficacy against pathogens and improved drug-target selectivity. The disadvantages, on the other hand are: certain lipids, especially charged lipids, become toxic in increased doses, sterilization is ...Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://www.researchgate.net/publication/322835130_An_Updated_Review_OnLiposomes_as_Drug_Delivery_System
Liposomes are most placed acquiring in pharma industries and very useful in the various drug delivery system used to target the drug to particular tissue.
https://www.researchgate.net/publication/281063035_Liposomes_as_a_Drug_Delivery_System
The discovery of phospholipids spontaneously forming spherical, self-closed bubbles known as liposomes, upon dispersion in water, ushered a new era in drug delivery technology.
https://www.intechopen.com/books/application-of-nanotechnology-in-drug-delivery/liposomes-as-potential-drug-carrier-systems-for-drug-delivery
Biological liposome stability plays important roles at various stages of drug delivery. However, liposomes are somewhat biologically unstable as a parenteral drug delivery system owing to their rapid uptake and clearance from circulation by cells of the mononuclear phagocytic system (MPS) located mainly in the liver and spleen [72, 73 ...Author: Melis Çağdaş, Ali Demir Sezer, Seyda Bucak
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599573/
Feb 22, 2013 · Thus, much attention on the use of drug delivery systems is focused on overcoming these problems, ultimately leading to the induction of maximal ability of anti-cancer drug. In this respect, a new model for cancer therapy using a novel drug delivery system, fusogenic liposome , was developed.Author: Abolfazl Akbarzadeh, Rogaie Rezaei-Sadabady, Rogaie Rezaei-Sadabady, Soodabeh Davaran, Sang Woo Joo,...
https://www.naturalmedicinejournal.com/blog/secret-effective-liposomal-delivery
In one study, cellular intake increased 9-fold as the liposome size was decreased from 236 nm to 97 nm, and cellular intake was increased 34-fold at 64 nm. 3 In addition, the therapeutic capabilities of a liposomal delivery system are also related to how fast the body clears the liposomes from the blood.
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