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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507026/
Jul 06, 2012 · Actually it is a modification of a technique called “biolistic,” originally developed for plant transgenesis, but now used for in vitro and in vivo gene delivery into mammalian cells too,[89,90] such as skin, mucosa, or surgically exposed tissue and especially for DNA-based immunization or vaccination.
https://www.hindawi.com/journals/jdd/2011/326497/
Anionic head groups are perhaps better suited for drug delivery. However, this does not preclude their use as gene delivery vehicles as work with divalent cations has shown. One must keep in mind all of the variables that come into play when using different gene delivery vectors.Author: Daniel A. Balazs, Wt. Godbey
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · The use of a cation is a recurring theme for virtually all chemically mediated gene delivery vectors, including polymers, lipids, and nondegradable nanoparticles. Between 8–18 carbons commonly comprise the hydrocarbon tails of lipids used for gene delivery. The tails are typically saturated, but a single double bond is occasionally seen.Author: Daniel A. Balazs, Wt. Godbey
https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
Liposomes as a gene delivery system ... In this paper, we have reviewed the major gene delivery vectors and recent improvements made in their design meant to overcome the issues that commonly ...
https://currentprotocols.onlinelibrary.wiley.com/doi/abs/10.1002/0471142905.hg1208s20
Gene therapy with nonviral, cationic liposomebased vectors has demonstrated promising results in a variety of in vivo models and some clinical trials. In contrast to viral vectors, cationic liposomebased vectors usually induce just mild inflammatory reactions, making them suitable for repeated injections in …Author: Mark Whitemore, Song Li, Leaf Huang
https://www.researchgate.net/publication/8927172_Cationic_Liposome-Mediated_Gene_Delivery_In_Vivo
The cationic liposomes provide a versatile in vivo delivery system for plasmid-based genes and anti-gene constructs. They offer a number of potential advantages over the competing viral vector ...
https://www.news-medical.net/whitepaper/20200206/Current-Gene-Delivery-Applications-and-Potential.aspx
Feb 06, 2020 · Liposome Gene Delivery Systems. ... clinical setting may only be realized after further research has explained the mechanisms of interaction between lipid vectors and gene expression in vivo…Author: BMG LABTECH Gmbh
https://www.sciencedirect.com/science/article/pii/S0076687903730341
The cationic liposomes provide a versatile in vivo delivery system for plasmid-based genes and anti-gene constructs. They offer a number of potential advantages over the competing viral vector systems, including relative ease and simplicity of formulation, an often reduced incidence of toxic inflammatory and immune-mediated anti-DNA carrier responses, and the ability to deliver very large (Mb ...Author: Yong Liu, Sylvia Fong, Robert J Debs
https://www.nature.com/articles/gt20175
Jan 17, 2017 · Optimization of methods to achieve mRNA-mediated transfection of tumor cells in vitro and in vivo employing cationic liposome vectors. Cancer Gene Ther 1994; 1 : 245–252. CASAuthor: S Guan, J Rosenecker
https://www.nature.com/articles/s41417-019-0141-7
Nov 02, 2019 · Liposomes are one of the most widely investigated carriers for CRISPR/Cas9 delivery. The surface properties of liposomal carriers, including …Author: Shuai Zhen, Shuai Zhen, Xu Li, Xu Li
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