Liposome Peptide Delivery

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Liposomal delivery of proteins and peptides.

    https://www.ncbi.nlm.nih.gov/pubmed/23092138
    EXPERT OPINION: The conclusion and expert opinion - conclusion sections discuss in detail troubleshooting aspects related to the use of liposomes as carriers for delivery of biopharmaceutical moieties and scrutinises the aspects behind the absence of a protein/peptide-containing liposome in market. PMID: 23092138 [Indexed for MEDLINE]Author: Janani Swaminathan, Carsten Ehrhardt

Oral peptide delivery by tetraether lipid liposomes ...

    https://www.sciencedirect.com/science/article/pii/S0378517311005187
    Initial approaches to the use of liposomes for oral peptide delivery were not very encouraging mostly due to a poor reproducibility of results (Chiang and Weiner, 1987b, Patel et al., 1982).Nevertheless, liposomes have some important advantages over other delivery systems as they are well characterised, have a good biocompatibility and high versatility (Jesorka and Orwar, 2008).Author: Johannes Parmentier, Bernhard Thewes, Felix Gropp, Gert Fricker

Cell penetrating peptide conjugated liposomes as ...

    https://www.sciencedirect.com/science/article/pii/S037851731500054X
    In this study, Polygonum aviculare L. extract, which has superior antioxidative and cellular membrane protective activity, was loaded onto cell penetrating peptide (CPP) conjugated liposomes to enhance transdermal delivery. The physical characteristics of typical liposomes and CPP-conjugated liposomes containing P. aviculare extract were evaluated. The particle sizes of both liposomes were ...Author: Soon Sik Kwon, Sun Young Kim, Bong Ju Kong, Kyeong Jin Kim, Geun Young Noh, Na Ri Im, Ji Won Lim, Ji...

Receptor-targeted liposome-peptide-siRNA nanoparticles ...

    https://www.nature.com/articles/srep21881
    Feb 24, 2016 · In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non …Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt

Preparation and optimization of anionic liposomes for ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5033054/
    As a negative control, intact cells received the FITC-short peptide (50 ng/ml) in the absence of liposomes. As a positive control for peptide delivery, cells were permeabilized using 0.15 mg/ml of digitonin (in PBS) for 5 min at 4 °C, followed by incubation with the FITC-labelled peptide (50 ng/ml).Author: Luís F. F. Neves, Jinghua Duan, Adrienne Voelker, Anil Khanal, Lacey McNally, Jill M. Steinbach-Rank...

Role of liposome and peptide in the synergistic ...

    https://www.nature.com/articles/srep09292
    Mar 19, 2015 · Aqueous preparations of liposome alone and a liposome-peptide mixture (LP; liposome: peptide ratio of 1:5.3) were also diluted in a final volume of 1 …Author: Mustafa M. Munye, Jascindra Ravi, Aristides D. Tagalakis, David McCarthy, Maxim G. Ryadnov, Stephen ...

TAT peptide on the surface of liposomes affords their ...

    https://www.pnas.org/content/98/15/8786
    Jul 17, 2001 · Liposome Integrity on Intracellular Delivery. To investigate whether TAT peptide-mediated internalization results in the intracellular delivery of intact liposomes, Rh-PE labeled liposomes with entrapped FITC-dextran were used. Upon the interaction of such liposomes with cells, cells were studied for both Rh and FITC fluorescence (Fig. 7). As ...Author: Vladimir P. Torchilin, Ram Rammohan, Volkmar Weissig, Tatyana S. Levchenko

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