We have collected information about Liposome Mediated Sirna Delivery for you. Follow the links to find out details on Liposome Mediated Sirna Delivery.
https://www.ncbi.nlm.nih.gov/pubmed/14652004
Dec 26, 2003 · However, the major obstacle to the use of siRNAs as therapeutics is the difficulty involved in effective in vivo delivery. We used a fluorescein-labeled siRNA to investigate cationic liposome-mediated intravenous and intraperitoneal delivery in adult mice. We show that this simple approach can deliver siRNAs into various cell types.Author: Mouldy Sioud, Dag R Sørensen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3052284/
Although the efficient delivery of siRNA-liposome complexes (lipoplexes) in vivo is limited by factors such as toxicity, enzymatic degradation, target specificity and poor vascular delivery, 11 several studies have described successful downregulation of target molecules using liposome-mediated delivery. The advantage of using liposomes as ...Author: M. Mikhaylova, I. Stasinopoulos, Y. Kato, Dmitri Artemov, Zaver M Bhujwalla
http://www.nature.com/articles/gt201088
Jun 03, 2010 · Liposome-mediated siRNA delivery in in vivo tumors. One of the limiting factors in the clinical use of siRNA technology is the delivery to target cells in vivo. We investigated whether ...Author: T Kato, A Natsume, H Toda, H Iwamizu, T Sugita, R Hachisu, R Watanabe, K Yuki, K Motomura, K Bankiew...
https://www.nature.com/articles/srep21881
Feb 24, 2016 · In conclusion, this is the first study to develop and show that receptor-targeted liposome-peptide-siRNA nanoparticles represent an efficient and safe non …Author: Yu-Wai-Man C, Tagalakis Ad, Manunta, Hart Sl, Khaw Pt
https://www.sciencedirect.com/science/article/pii/S0168365919307230
Exosome-mediated siRNA delivery to suppress postoperative breast cancer metastasis. Author links open overlay panel Liuwan Zhao a 1 Chunyan Gu b 1 Ye Gan a Lanlan Shao a Hongwei Chen c Hongyan Zhu a. ... and screen out the optimal weight ratio of CBSA/siRNA and liposome. Similarly, we studied the size, zeta potential, ...Author: Liuwan Zhao, Chunyan Gu, Ye Gan, Lanlan Shao, Hongwei Chen, Hongyan Zhu
https://onlinelibrary.wiley.com/doi/full/10.1111/dgd.12123
Therefore, cationic liposome‐mediated local administration of Mst‐siRNA could increase muscular size and improve muscle activity. Since cationic liposomes delivered siRNA to muscles effectively and are safe and cost‐effective, they may represent a therapeutic tool for use in treating muscular diseases.Author: Hiroyo Mori, Nobuhiko Kawai, Nao Kinouchi, Natsuko Hichijo, Tatsuhiro Ishida, Emi Kawakami, Sumihare...
https://www.sciencedirect.com/science/article/pii/S0378517311010477
siRNA has been touted as a therapeutic molecule against genetic diseases, which include cancers. But several challenging issues remain in order to achieve efficient systemic siRNA delivery and a sufficient therapeutic effect for siRNA in vivo.Cationic liposome shows promise as a carrier for nucleic acids, as it can selectively bind to angiogenic tumor blood vessels.Author: Tatsuaki Tagami, Takuya Suzuki, Mariko Matsunaga, Kazuya Nakamura, Naoto Moriyoshi, Tatsuhiro Ishida...
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