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https://www.sciencedirect.com/topics/neuroscience/liposomal-gene-delivery-system
They saw no evidence of cellular toxicity, whereas lipofectin caused a significant decrease in cell viability. This same group has used the HVJ liposome delivery system to transfer several other genes to vascular cells, both in vitro and in vivo.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Most liposomal formulations used for gene delivery consist of a combination of charged lipids and neutral helper lipids [ 12, 22 – 24, 26, 28 ]. The neutral helper lipids used are often dioleoylphosphatidylethanolamine (DOPE), which is the most widely used neutral helper lipid, or dioleoylphosphatidylcholine (DOPC).Author: Daniel A. Balazs, Wt. Godbey
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3687232/
Nov 27, 2012 · Lipid emulsions are also used in gene delivery which is found to be superior to liposomal delivery. Liposomal gene delivery systems can be prepared by hydrating the lipid film in the presence of DNA, high molecular weight DNA is entrapped in egg phosphatidylcholine liposomes and metaphase chromosomes incorporated in egg phosphatidylcholine-cholesterol (7:2, mol/mol) liposomes.
https://www.slideshare.net/DurgaBhavani60/liposomal-gene-delivery-system
Jul 14, 2019 · LIPOSOMAL GENE DELIVERY SYSTEMS: INTRODUCTION: Liposomes have been explored as a delivery system for DNA as early as in 1979. The encapsulation of plasmid DNA into liposomes and the introduction of poliovirus RNA and SV40 DNA into cells via liposomes were reported between 1979 and 1980. These are vesicles that can easily merge with the cell membrane. since, …
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200004
Many liposome-based DNA delivery systems have been described, including molecular components for targeting given cell surface receptors or for escaping from the lysosomal compartment. Another recent technology using cationic lipids has been evaluated and has generated substantial interest in this approach to gene transfer.
https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
Many liposome-based DNA delivery systems have been described, including molecular components for targeting given cell surface receptors or for escaping from the lysosomal compartment.
https://www.hindawi.com/journals/jdd/2011/326497/
Liposomes are often used to deliver a molecular cargo such as DNA for therapeutic benefit. The lipids used to form such lipoplexes can be cationic, anionic, neutral, or a mixture thereof. Herein physical packing parameters and specific lipids used for gene delivery will be discussed, with lipids classified according to overall charge.Author: Daniel A. Balazs, Wt. Godbey
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
A number of liposomes (lipidic nanoparticles) are on the market, and many more are in the pipeline. Lipidic nanoparticles are the first nanomedicine delivery system to make the transition from concept to clinical application, and they are now an established …Author: Theresa M. Allen, Pieter R. Cullis
https://www.slideshare.net/snehaldhobale7/liposomes-a-novel-drug-delivery-system-40045718
Oct 08, 2014 · Liposomes- A Novel Drug Delivery System Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. If you continue browsing the site, you agree to the use of cookies on this website.
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