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https://www.sciencedirect.com/science/article/pii/S1046202306001605
The use of liposomal agents enables the delivery of multiple Ags and/or immunomodulatory agents to immune cells such as DCs, and could be a particularly effective strategy for the development of vaccines against complex pathogens with immune evasion strategies, such as TB and malaria.Author: Joseph G. Altin, Christopher R. Parish
https://www.researchgate.net/publication/6796335_Liposomal_vaccines-Targeting_the_delivery_of_antigen
Liposomal formulations are an important carrier system frequently used for delivery of antigen because the specific properties of this component such as lipid composition, charge, size,...
https://researchers.anu.edu.au/publications/11060
Liposomal vaccines - targeting the delivery of antigen Citation Altin, J & Parish, C 2006, 'Liposomal vaccines - targeting the delivery of antigen', Methods, vol. 40, pp. 39-52.
https://openresearch-repository.anu.edu.au/handle/1885/79333
Altin, Joseph; Parish, Christopher. Description. Vaccines that can prime the adaptive immune system for a quick and effective response against a pathogen or tumor cells, require the generation of antigen (Ag)-specific memory T and B cells.Author: Joseph G. Altin, Christopher R. Parish
https://www.deepdyve.com/lp/elsevier/liposomal-vaccines-targeting-the-delivery-of-antigen-8iCZU0sl0e
Sep 01, 2006 · Liposomal vaccines—targeting the delivery of antigen The unique ability of dendritic cells (DCs) to activate naïve T cells, implies a key role for DCs in this process. The generation of tumor-specific CD8 + cytotoxic T cells (CTLs) is dependent on both T cell stimulation with Ag (peptide–MHC-complexes) and costimulation.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4212474/
Liposome-mediated effects of antigen uptake, trafficking, processing and presentation. As the majority of vaccines are administered by intramuscular or subcutaneous injection, liposome properties play a major role in local tissue distribution, retention, trafficking, uptake and processing by APCs.Author: Reto A. Schwendener
https://pubs.acs.org/doi/10.1021/acs.biochem.9b00402
Antigen encapsulation into pH-dependent liposomes can control the delivery of an antigen to defined cellular compartments and therefore direct the immune response to CD4 + or CD8 + T-cell activation.Author: Jessica Schulze, Jessica Schulze, Mareike Rentzsch, Dongyoon Kim, Lydia Bellmann, Patrizia Stoitzner...
https://www.researchgate.net/publication/10932974_Liposomal_delivery_of_antigen_to_human_dendritic_cells
Liposomal delivery of antigen to human dendritic cells Article in Vaccine 21(9-10):883-90 · March 2003 with 261 Reads How we measure 'reads'
https://www.sciencedirect.com/science/article/pii/S0142961217306142
Herein, we introduce a versatile nanovaccine of liposomes-coated gold nanocages (Lipos-AuNCs) modified with DCs specific antibody aCD11c for targeted delivery of adjuvant MPLA and melanoma antigen peptide TRP2 to promote the activation and maturation of DCs, and enhance tumor specific T lymphocytes responses.Author: Ruijing Liang, Jun Xie, Jun Xie, Jun Li, Ke Wang, Liping Liu, Yujie Gao, Mubashir Hussain, Guanxin S...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4810083/
Mar 10, 2016 · The use of liposomes as a delivery system thus serves to ensure co-delivery of immunostimulators and antigen, while at the same time minimizing the detrimental effects of poly(I:C). TLR7 recognizes single-stranded RNA, but the most used agonists are the synthetic imidazoquinoline derivatives, imiquimod and resiquimod [ 89 ].Author: Signe Tandrup Schmidt, Camilla Foged, Karen Smith Korsholm, Thomas Rades, Dennis Christensen
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