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https://www.ncbi.nlm.nih.gov/pubmed/23092138
Liposomal delivery of proteins and peptides. ... INTRODUCTION: A number of delivery issues exist for biotech molecules including peptides, proteins and gene-based medicines that now make up over 60% of the drug pipeline. The problems comprise pharmaceutical ad biopharmaceutical issues.Author: Janani Swaminathan, Carsten Ehrhardt
https://www.researchgate.net/publication/232057603_Liposomal_Delivery_of_Peptides_and_Proteins
In this contribution examples of liposomal delivery approaches for peptides and proteins will be briefly described. These examples include the parenteral delivery of vasopressin, interleukin-2 ...
https://www.researchgate.net/publication/232646907_Liposomal_delivery_of_proteins_and_peptides
Introduction: A number of delivery issues exist for biotech molecules including peptides, proteins and gene-based medicines that now make up over 60% of the drug pipeline.
https://www.sciencedirect.com/science/article/pii/S2162253116300294
Intracellular delivery of functional proteins provides a potential tool to replace missing, dysfunctional and poorly expressed proteins or antagonize key intracellular pathways. Protein-based therapeutics is a promising approach for several biomedical applications including stem cell engineering, imaging, and signaling studies.Author: Benoît Chatin, Benoît Chatin, Mathieu Mével, Mathieu Mével, Julie Devallière, Julie Devallière, Laur...
https://www.tandfonline.com/doi/abs/10.1517/17425247.2012.735658
Sep 15, 2014 · Introduction: A number of delivery issues exist for biotech molecules including peptides, proteins and gene-based medicines that now make up over 60% of the drug pipeline. The problems comprise pharmaceutical ad biopharmaceutical issues. One of the common approaches to overcome these issues is the use of a carrier and liposomes as carriers have been investigated extensively over …Author: Janani Swaminathan, Carsten Ehrhardt
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857543/
2.0 PEGYLATION. The conjugation of polymers to proteins had been in practice since the 1950s, but it was the development of PEGylation that provided the real breakthrough in enhancing the pharmaceutical properties of proteins and peptides in a viable manner 6 PEGylation, the covalent attachment of PEG moieties to a therapeutic agent, was first reported in the 1970s. 7, 8 Experiments attempting ...Author: Dipak S. Pisal, Matthew P. Kosloski, Sathy V. Balu-Iyer
https://www.sciencedirect.com/science/article/pii/S0168365996015830
3. Ongoing projects and outline of this report. Our groups study different aspects of liposomal delivery of peptides and proteins. The projects under investigation are presented in Table 1.They are classified on the basis of (1) the route of liposome administration, (2) …Author: D.J.A Crommelin, T Daemen, G.L Scherphof, M.H Vingerhoeds, J.L.M Heeremans, C Kluft, G Storm
https://www.ondrugdelivery.com/pulmonary-delivery-antimicrobial-peptides/
nanocarriers for pulmonary delivery of peptides Figure 2: Schematic illustration of the possible action mechanisms of antimicrobial peptides interacting with cell membranes. 13 As soon as they enter the body, AMPs, as well as other peptides and proteins, are attacked by proteases, which break them down into amino acids and shorter fragments.
https://en.wikipedia.org/wiki/Liposome
A liposome is a spherical vesicle having at least one lipid bilayer.The liposome can be used as a vehicle for administration of nutrients and pharmaceutical drugs. Liposomes can be prepared by disrupting biological membranes (such as by sonication).. Liposomes are most often composed of phospholipids, especially phosphatidylcholine, but may also include other lipids, such as egg ...
https://sites.ualberta.ca/~csps/JPPS5(3)/J.Samuel/peptide.pdf
peutic peptides. Similarly, the use of RP-HPLC to deter-mine peptide quantity is a standard procedure that has yet to be carefully examined in the framework of liposomal and polymeric formulations. The purpose of this series of investigations was to determine how best to extract a vari-ety of peptides and lipopeptides from vaccine formula-
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