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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664963/
Dec 01, 2015 · With non-cross resistance properties and an enhanced cellular uptake and retention, annamycin's efficacy and anti-tumor activity is enhanced with the use of a targeted liposomal-based delivery system (Zou et al., 1994). These and more liposomal-based drugs that are FDA approved or currently in clinical trials are summarized in Table Table1 1.Author: Lisa Sercombe, Tejaswi Veerati, Tejaswi Veerati, Fatemeh Moheimani, Sherry Y. Wu, Anil K. Sood, Susa...
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
Liposomal drug delivery systems are very effective in the delivery of vaccines and genes due to their adjuvant property and targeting ability which elicit the immune response of the body through antibody formation and corrected gene inputs. Along with this, the mechanism of vaccine and gene delivery is …
https://www.omicsonline.org/open-access/liposomes-for-drug-delivery-2155-952X276-97370.html
Sustained release drug delivery. To achieve the optimum therapeutic efficacy, which requires a prolonged plasma concentration at therapeutic levels, liposomes provide sustained release of target drugs . Drugs like cytosine Arabinoside can be encapsulated in liposomes for sustained release and optimized drug release rate in vivo.Author: Durgavati Yadav, Kumar Sandeep, Deepak Pandey, Ranu Kumari Dutta
https://mct.aacrjournals.org/content/5/7/1639
Jul 01, 2006 · Liposomal delivery is therefore a means to modify the pharmacokinetic and pharmacodynamic properties of therapeutic agents. Such modifications can, in some settings, improve the therapeutic efficacy of anticancer drugs and reduce or modulate their toxicity profile.Author: Robert J. Lee
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017847/
Apr 14, 2018 · In this context, encapsulation of anti-cancer drugs within the liposomal system offers secure platforms for the targeted delivery of anti-cancer drugs for the treatment of cancer. This, in turn, can be helpful for reducing the cytotoxic side effects of anti-cancer drugs on normal cells. This short-review focuses on the use of liposomes in anti ...Author: Temidayo O. B. Olusanya, Rita Rushdi Haj Ahmad, Daniel M. Ibegbu, James R. Smith, Amal Ali Elkordy
https://www.sciencedirect.com/science/article/pii/S0169409X12002980
Within a few years, a variety of enclosed phospholipid bilayer structures consisting of single bilayers, initially termed ‘bangosomes’ and then ‘liposomes’ , were described , and the early pioneers such as Gregory Gregoriadis, established the concept that liposomes could entrap drugs and be used as drug delivery systems , , , .Author: Theresa M. Allen, Pieter R. Cullis
https://www.uspharmacist.com/article/drug-delivery-systems-for-cancer-therapeutics
Sep 20, 2011 · Two types of drug delivery systems—liposomal and albumin nanoparticle drugs—have caused notable improvement in the therapeutic index of anticancer agents; however, the lack of success in improving overall survival makes it imperative to further develop and refine drug delivery systems.
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