We have collected information about Lipoplexes For Gene Delivery for you. Follow the links to find out details on Lipoplexes For Gene Delivery.
http://www.genetherapynet.com/non-viral-vectors/lipoplexes-and-polyplexes.html
To improve the delivery of the new DNA into the cell, the DNA must be protected from damage and its entry into the cell must be facilitated. To this end new molecules, lipoplexes and polyplexes, have been created that have the ability to protect the DNA from undesirable degradation during the tr...
https://www.sciencedirect.com/science/article/pii/S0928098710001028
While lipids that facilitate transformation of lipoplexes to non-bilayer phases mediate high transfection activity in vitro, lipids, like cholesterol, that confer stability in serum, are more suitable for gene delivery in vivo. The efficiency of polyplex-mediated transfection depends on the ability of the polymer to condense DNA, while allowing ...Author: Conchita Tros de Ilarduya, Yan Sun, Nejat Düzgüneş
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
Dec 15, 2010 · Perhaps due to the natural presence of these specific phospholipids in the host cell membrane, gene delivery via lipoplexes with net negative surface potentials has been associated with lower clearance and phagocytosis by macrophages, which is consistent with favorable biocompatibility .Author: Daniel A. Balazs, Wt. Godbey
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3771368/
The mechanism of gene delivery by cationic lipoplexes has been reviewed [112,113] and it is now generally accepted that liposome-mediated gene transfer proceeds primarily through endocytosis [114– 116] . Following cellular uptake, lipoplexes can destabilize the endosomal membrane, resulting in a flip-flop reorganization of the membrane ...Author: Xiao-Xiang Zhang, Thomas J. McIntosh, Mark W. Grinstaff
https://www.sciencedirect.com/science/article/abs/pii/S0928098710001028
Jun 14, 2010 · Gene delivery by lipoplexes and polyplexes. ... Abstract. Gene therapy has emerged as a promising approach for the treatment or prevention of acquired and genetic diseases. At the present time, major somatic gene transfer approaches employ either viral or non-viral vectors. Viral vectors show high gene transfer efficiency, but are deficient in ...Author: Conchita Tros de Ilarduya, Yan Sun, Nejat Düzgüneş
https://www.heighpubs.org/jgmgt/jgmgt-aid1002.php
Jun 29, 2017 · For gene delivery, HA is usually coated onto surface of cationic lipoplexes or polyplexes by electrostatic interactions to shield the positive charge. HA is a prominent component of the microenvironment in most malignant tumors, and CD44 is the major receptor for HA.Author: Yoshiyuki Hattori
https://www.hindawi.com/journals/jdd/2011/326497/
Perhaps due to the natural presence of these specific phospholipids in the host cell membrane, gene delivery via lipoplexes with net negative surface potentials has been associated with lower clearance and phagocytosis by macrophages, which is consistent with favorable biocompatibility .Author: Daniel A. Balazs, Wt. Godbey
https://www.nature.com/articles/3301840
Jan 13, 2003 · Optimization of asialofetuin-lipoplexes. In order to obtain efficient complexes for gene delivery in vitro and in vivo, lipoplexes were prepared in the presence of different amounts of AF.The ...Author: M A Arangoa, N Düzgüneş, C Tros de Ilarduya
https://www.researchgate.net/publication/262177998_Lipoplexes_and_Polyplexes_Gene_Delivery_Applications
This formulation improved gene delivery showed by conventional lipoplexes or polyplexes resulting an efficient, simple and nontoxic method for gene delivery of therapeutic genes in vitro and very ...
https://www.researchgate.net/publication/42832762_Gene_delivery_by_lipoplexes_and_polyplexes
Gene therapy has emerged as a promising approach for the treatment or prevention of acquired and genetic diseases. At the present time, major somatic gene transfer approaches employ either viral ...
Searching for Lipoplexes For Gene Delivery?
You can just click the links above. The data is collected for you.
