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https://www.pharmaexcipients.com/excipient-suppliers-list/gattefosse-lipid-excipients/
Lubricant for challenging pharmaceutical tablets and capsules, with inert excipients eliminating the drug-excipient incompatibility issues. Topical drug delivery Functional lipid excipients are used to formulate creams, lotions, ointments, oily and aqueous gels and foams.
http://www.americanpharmaceuticalreview.com/pfu/7964385/soids/1402542/Excipient_Search/Lipid
33 rows · Lipid Excipients. The use of lipids in sustained release formulations is growing. Lipid …
https://www.pharmaexcipients.com/news/cphi/lipid-excipients-for-cannabinoid-drug-products-2/
Rectal and Vaginal Delivery. Solid lipid excipients, known in pharmacopoeia as “Hard fat” commonly constitute the “base” or the medium for delivery of drugs in suppository (rectal) or pessary (vaginal). In order to meet the formulation needs for different drugs, dose variations, mold types, and manufacturing speeds, Gattefossé hasAuthor: Markus Köbel
https://www.ondrugdelivery.com/synergising-excipients-to-boost-skin-delivery/
Citation: Morin C, “Synergising Excipients to Boost Skin Delivery”. ONdrugDelivery Magazine, Issue 99 (Aug 2019), pp 54-58. Cécile Morin and Delphine Marchaud discuss combining polar and apolar excipients in topical formulations in order produce synergies that maximise the performance of the drug.
https://www.hindawi.com/journals/jphar/2014/801820/
In vitro evaluation of lipid-based drug delivery systems can be done with the use of lipid digestion models. In order to assess the performance of an excipient during formulation development and to predict in vivo performance, it is necessary to design an in vitro dissolution testing method.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6406477/
Feb 13, 2019 · Diagram of drug delivery system for oral lipid-based formulation (LBF) drug and its absorption. LBF drug enters the stomach where gastric lipase hydrolysed and stabilised the drug in the stomach, due to the presence of its excipient and surfactant. An excipient is defined as the drug carrier, usually lipids that help to solubilise drugs.Author: Danial Efendy Goon, Siti Hamimah Sheikh Abdul Kadir, Normala Ab Latip, Sharaniza Ab. Rahim, Musalmah...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · During this process, along with the lipid excipients, solid carriers like silicon dioxide can be used. Gelucire (lipid excipient) enhances the drug release process by forming hydrogen bonds with the active substance, leading to the formation of stable solids of amorphous drug in microparticles [ …Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.sciencedirect.com/science/article/pii/S2211383513000919
The availability of novel lipid excipients with acceptable regulatory and safety profiles coupled with their ability to enhance oral bioavailability has helped in the development of lipid based formulations as a means for drug delivery. Lipid-based drug delivery (LBDD) systems have gained much importance in the recent years due to their ability to improve the solubility and bioavailability of drugs with poor …Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/lipid-based-drug-delivery-system
Lipid-based drug delivery systems showed great potential in overcoming problems of low bioavailability of poorly soluble drugs. Since mechanisms responsible for improving drug bioavailability are quite different from other delivery systems, these systems require application of specific characterization methods, which can simulate what happens with formulation during transit through GIT.
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