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https://www.sciencedirect.com/science/article/pii/S2211383513000919
Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address such challenges. Encapsulating or solubilizing the drug in lipid excipients can lead to increased solubilization and absorption, resulting in enhanced bioavailability.Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://www.hindawi.com/journals/jphar/2014/801820/
The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs. Lipid-based ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · The principle objective of formulation of lipid-based drugs is to enhance their bioavailability. The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the ...Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
Jason M. LePree, RPh, PhD, reviews the causes of poor bioavailability for drugs and provides an introduction to lipid-based drug delivery systems, and how the formulation approach can be used to overcome impediments to good bioavailability of therapeutic actives.
https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/lipid-based-drug-delivery-system
This chapter describes DepoFoam-mediated drug delivery into cerebrospinal fluid (CSF). DepoFoam is a lipid-based drug delivery system that can deliver a variety of water-stable molecules into the CSF over a prolonged period following a single injection. DepoFoam is composed of microscopic spherical particles, each enclosing multiple ...
http://www.americanpharmaceuticalreview.com/Featured-Articles/341191-Why-Consider-a-Lipid-Based-Drug-Delivery-System-LBDDS/
Aug 15, 2017 · Approximately 90 percent of molecules in the discovery pipeline, and approximately 40 percent of drugs with market approval, are poorly water soluble. 2 Advanced delivery technologies, like lipid-based systems, are an alternative solution to safely and effectively deliver the proper therapeutic dose to patients. Unlike conventional tablets or powder-filled capsules, LBDDS can present the drug ...Author: John Lipari
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154489/
Aug 04, 2018 · Introduction. Rapid advances in the field of lipid nanoparticle formulations (LNFs) have caused a revolution to offer superior drug delivery systems for the mitigation of numerous dreadful diseases particularly in the area of pharmaceutical sciences.Author: Subham Banerjee, Amit Kundu
https://www.hindawi.com/journals/ap/2014/574673/
1.1. Lipid Based Vesicular Drug Delivery System. Vesicular drug delivery system can be defined as highly ordered assemblies consisting of one or more concentric bilayers formed as a result of self-assembling of amphiphilic building blocks in presence of water.Author: Shikha Jain, Vikas Jain, S. C. Mahajan
https://www.intechopen.com/books/recent-advances-in-novel-drug-carrier-systems/lipid-nanoparticulate-drug-delivery-systems-a-revolution-in-dosage-form-design-and-development
Nanoparticulate drug delivery systems (DDS) have attracted a lot of attention because of their size-dependent properties. Among the array of nanoparticles being currently investigated by pharmaceutical scientists, lipid nanoparticles have taken the lead because of obvious advantages of higher degree of biocompatibility and versatility.Author: Anthony A. Attama, Mumuni A. Momoh, Philip F. Builders
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