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https://www.sciencedirect.com/science/article/pii/S2211383513000919
Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address such challenges. Encapsulating or solubilizing the drug in lipid excipients can lead to increased solubilization and absorption, resulting in enhanced bioavailability.Author: Sandeep Kalepu, Mohanvarma Manthina, Veerabhadhraswamy Padavala
https://drug-dev.com/lipid-based-delivery-are-lipid-based-drug-delivery-systems-in-your-formulation-toolbox/
Lipid-based drug delivery systems (LBDDS) is a wide-ranging designation for formulations containing a dissolved or suspended drug in lipidic excipients. Lipids are esters of fatty acids – lipophilic hydrocarbon chains linked to a hydrophilic group like glycerol, polyglycerol, or polyalcohol …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4590796/
May 19, 2014 · Routes like oral, parenteral, ocular, intranasal, dermal/transdermal, and vaginal can be for the administration of the lipid-based drug delivery systems (LBDDS) [4, 5]. However, oral route is the most preferred route because of the properties like noninvasiveness, less expensive, and less prone to side effects, such as injection-site reactions.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
https://www.sciencedirect.com/science/article/pii/S1740674912000145
Mechanisms of lipid-based formulations to improve oral drug absorption and case studies Effects of lipid-based excipients. The physical state of a lipophilic drug is important for the in vivo performance of any oral dosage form. Because the drug is generally solubilized in LBDDS, no dissolution step is needed.Author: Martin Kuentz
https://www.jgtps.com/admin/uploads/cjgGFf.pdf
drug, mean droplet diameter. Lipid excipient increases the oral absorption by retarding the gastric emptying. Various marketed formulations are discussed in this review. Lipid based drug delivery system delivers the proteins and peptide by solid lipid nanoparticles, liposomes, these are potential for enhancing oral delivery.File Size: 145KB
https://www.pharmaexcipients.com/news/cphi/lipid-excipients-for-cannabinoid-drug-products-2/
These properties render cannabinoids as excellent candidates for Lipid-Based Drug Delivery (LBDD). The Benefits of Lipid Excipients in Oral Drug Delivery. Lipid formulations are shown to improve the bioavailability of cannabinoids by improving solubility, intestinal permeability, and enhancement of the lymphatic route of absorption. Among the keyAuthor: Markus Köbel
https://www.pharmaexcipients.com/wp-content/uploads/2019/02/brochure_gattefosse-lipid-excipients-for-cannabinoid-drug-products.pdf
Oral Drug Delivery. 13. Alternative Drug Delivery Routes. 11. Dermal Drug Delivery. 16. Technical Support. 5. Properties of Cannabinoids. The Benefits of Lipid Based Excipients in: This brochure provides an overview of the formulation opportunities with Gattefossé excipients in developing medicinal cannabinoids for oral, topical, transdermal, and
https://www.hindawi.com/journals/jphar/2014/801820/
The use of lipids in drug delivery is no more a new trend now but is still the promising concept. Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address challenges like the solubility and bioavailability of poorly water-soluble drugs.Author: Kent Jørgensen, Jesper Davidsen, Charlotte Vermehren, Sven Frøkjær, Ole G. Mouritsen
http://www.americanpharmaceuticalreview.com/Featured-Articles/347220-The-Truths-and-Myths-of-Oral-Lipid-Based-Drug-Delivery-Systems/
Lipid-based drug delivery systems (LBDDS) are the most well studied and well established formulation approaches for addressing solubility and permeability issues. 1 Even though LBDDS are well documented in literature, the pharmaceutical industry has …
https://www.researchgate.net/publication/259171198_Oral_lipid-based_drug_delivery_systems_-_An_overview
Lipid-based drug delivery systems (LBDDS) are one of the emerging technologies designed to address such challenges. Encapsulating or solubilizing the drug in lipid excipients can lead to increased solubilization and absorption, resulting in enhanced bioavailability.
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