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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2774780/
in vivo delivery of shrna expression lentiviral vectors One of the very desirable features of lentiviral vectors is their ability to transduce non-dividing cells such as neurons. Through the use of stereotactic injection device, concentrated lentiviral particles can be injected into define sites of the brain [ 27 ].Author: Oded Singer, Inder M. Verma
https://www.thermofisher.com/us/en/home/life-science/rnai/virus-based-rnai-analysis/lentiviral-shrna-and-mirna-analysis.html
13 rows · Viral delivery can be the best option in virtually any mammalian cell type, including hard-to …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679364/
For most untransfectable cells, adenoviral, retroviral, or lentiviral-based shRNA technology remains the only viable technology for the successful delivery of RNAi. For these reasons, this article focuses primarily on methodologies applicable to shRNA, though many of the suggestions may also be useful for siRNA.Author: Chris B. Moore, Elizabeth H. Guthrie, Max Tze-Han Huang, Debra J. Taxman
https://en.wikipedia.org/wiki/File:ShRNA_Lentivirus.svg
English: Lentiviral delivery of shRNA expression construct for stable integration and expresion of shRNA. ShRNA processing and inhibitory mechanisms. This W3C-unspecified vector image was created with Adobe Illustrator . This file is licensed under the Creative Commons Attribution-Share Alike 3.0 Unported license.
https://www.origene.com/products/cdna-clones/lentiviral-particles
Lentiviral vectors as gene delivery tool are modified from HIV-1, with many of the viral genes removed. The lentiviral vector only contain the LTRs and the packaging signal, ψ. Lentiviral packaging genes are provided on separate plasmids, so the pseudo lentiviral particles are replication deficient.
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