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https://link.springer.com/chapter/10.1007/12_2017_11
Apr 23, 2017 · Abstract. Various drug delivery systems are being rapidly developed for controlled drug release, improved efficacy, and reduced side effects with the goal of improving quality of life for patients and curing disease. Poly(lactic acid) (PLA) possesses numerous advantages compared with other polymers, including biocompatibility, biodegradability,...Author: Jiannan Li, Jiannan Li, Jianxun Ding, Tongjun Liu, Jessica F. Liu, Lesan Yan, Xuesi Chen
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6883978/
Nov 11, 2019 · Colorectal Cancer Therapy Using a Pediococcus pentosaceus SL4 Drug Delivery System Secreting Lactic Acid Bacteria-Derived Protein p8 Byung Chull An , Yongku Ryu , Yeo-Sang Yoon , Oksik Choi , Ho Jin Park , Tai Yeub Kim , Song-In Kim , Bong-Kyu Kim , and Myung Jun Chung *Author: Byung Chull An, Yongku Ryu, Yeo-Sang Yoon, Oksik Choi, Ho Jin Park, Tai Yeub Kim, Song-In Kim, Bong-...
https://anis.au.dk/en/current-news/news/show/artikel/bakterier-som-maalrettede-budbringere/
Scientists from Aarhus University are leading a project to develop the system so that lactic acid bacteria can be used to deliver drugs directly to the intestinal cells to combat the chronic inflammatory bowel disease called Crohn's disease more efficiently. Lactic acid bacteria have previously been demonstrated to be suitable carriers of drugs.
https://www.hindawi.com/journals/jnm/2017/6847297/
The majority of properties of minicells generated by lactic acid bacteria are nanosized, round shape which is suitable for drug delivery. Multifunctional nanoparticles delivering multiple drugs are now being developed for enhanced detection and treatment of cancer. Furthermore, lactic acid bacteria are used in pharmaceutical field and food industry.Author: Huu Ngoc Nguyen, Santa Romero Jovel, Tu Hoang Khue Nguyen
https://www.ncbi.nlm.nih.gov/pubmed/26377321
Sep 16, 2015 · Lactic acid bacteria (LAB) have a long history of safe exploitation by humans, being used for centuries in food production and preservation and as probiotic agents to …Author: Olivia Cano-Garrido, Olivia Cano-Garrido, Joaquin Seras-Franzoso, Joaquin Seras-Franzoso, Elena Garc...
https://microbialcellfactories.biomedcentral.com/articles/10.1186/s12934-015-0313-6
Given the need to develop an alternative route for the administration, as well as a safety delivery platform, lactic acid bacteria (LAB) have appeared as an appealing option for the production and delivery of therapeutic molecules and antigens of interest [ 4 ]. This heterogeneous group of Gram-positive bacteria,...Author: Olivia Cano-Garrido, Olivia Cano-Garrido, Joaquin Seras-Franzoso, Joaquin Seras-Franzoso, Elena Garc...
https://www.researchgate.net/publication/319534159_Nanosized_Minicells_Generated_by_Lactic_Acid_Bacteria_for_Drug_Delivery
Organic and inorganic nanoparticles have been developed for drug delivery systems. Many delivery systems are through clinical stages for development and market. Minicell, a nanosized cell generated by bacteria, is a potential particle for drug delivery because of its size,...
https://www.sciencedaily.com/releases/2018/12/181220122606.htm
Dec 20, 2018 · An interdisciplinary team of three Virginia Tech faculty members affiliated with the Macromolecules Innovation Institute has created a drug delivery …
https://www.nature.com/articles/s41598-017-02591-6
May 23, 2017 · The use of live genetically modified bacteria as delivery vehicles for the in situ delivery of therapeutics has to date relied on the use of specific commensal or food-grade bacteria…Author: Udo Wegmann, Ana Lucia Carvalho, Ana Lucia Carvalho, Martin Stocks, Simon R. Carding, Simon R. Cardi...
https://www.pnas.org/content/115/8/1895
Feb 20, 2018 · Bacteria-produced lactic acid reduced the local pH, which inhibited the peptidase CD26 and consequently enhanced the availability of bioactive CXCL12. Importantly, treatment with CXCL12-delivering Lactobacilli also improved wound closure in mice with hyperglycemia or peripheral ischemia, conditions associated with chronic wounds, and in a human skin wound model.Author: Evelina Vågesjö, Emelie Öhnstedt, Anneleen Mortier, Hava Lofton, Fredrik Huss, Fredrik Huss, Paul Pr...
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