Intravenous Diltiazem Q6 Hours

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Atrial Fibrillation – Rate Control Drugs

    https://www.uwhealth.org/cckm/cpg/cardiovascular/related/Atrial-Fibrillation-Mgt---Rate-Control-Drugs-190312.pdf
    Diltiazem IV Dosing 0.25mg/kg (Max dose: 25mg) IV bolus x1. Start drip at 5mg/hr. Consider addition 30mg PO IR Diltiazem q6 hours or home dose to reduce need for drip. Drip can be titrated to 15mg/hr, with re-bolus of 0.25mg/kg with each increase. IV to PO diltiazem: Oral dose = (IV drip rate [in mg/hr] x …

DailyMed - DILTIAZEM HYDROCHLORIDE injection

    https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=5e36488b-8f2d-4dc9-b803-af1829e6fdd0
    Oct 08, 2020 · After constant rate intravenous infusion to healthy male volunteers, diltiazem exhibits nonlinear pharmacokinetics over an infusion range of 4.8 to 13.2 mg/h for 24 hours. Over this infusion range, as the dose is increased, systemic clearance decreases from 64 to 48 L/h while the plasma elimination half-life increases from 4.1 to 4.9 hours.

Emergency Department Management of Atrial …

    https://www.uwhealth.org/cckm/cpg/cardiovascular/related/Atrial-Fibrillation-Mgt---Emergency-Department-Management-of-Atrial-Fibrillation-Algorithm-190312.pdf?download=true
    Diltiazem 0.25 mg/kg (Max dose 25 mg) IV bolus x1. Start drip at 5 mg/hr. Consider addition 30mg PO IR diltiazem q6 hours or home dose to reduce need for drip. Drip can be titrated to 15 mg/hr, with re‐bolus 0.25 mg/kg with each increase.Author: Le Katherine J

Control of heart rate during transition from intravenous ...

    https://pubmed.ncbi.nlm.nih.gov/8960583/
    Oral long-acting diltiazem (diltiazem CD 180, 300, or 360 mg/24 hours) was administered in patients in whom stable heart rate control was attained during constant infusion. Intravenous diltiazem infusion was discontinued 4 hours after the first oral dose, and patients were monitored during 48 subsequent hours of "transition" to oral therapy.Cited by: 11

Intravenous Continuous Infusion vs. Oral Immediate …

    https://pubmed.ncbi.nlm.nih.gov/29560075/
    When we performed a multivariate analysis adjusted for race and initial HR, PO was still less likely to be associated with treatment failure than IV with an OR of 0.4 (95% CI [0.15, 0.94], p = 0.041). The median dose of PO diltiazem and IV continuous infusion diltiazem at four hours …

Diltiazem Dosage Guide + Max Dose, Adjustments - …

    https://www.drugs.com/dosage/diltiazem.html
    Mar 10, 2021 · -Initial bolus dose: 0.25 mg/kg IV as a bolus administered over 2 minutes. After 15 minutes, a second bolus of 0.35 mg/kg IV (administered over 2 minutes) may be used if necessary. Continuous Infusion:-The continuous infusion should begin immediately following a bolus injection of 0.25 mg/kg IV OR 0.35 mg/kg IV administered over 2 minutes.

Diltiazem (Cardizem) Infusion Protocol

    http://www.lowerumpquahospital.org/wp-content/uploads/2017/06/Diltiazem-Cardizem.pdf
    Diltiazem (Cardizem) Infusion Protocol . Lower Umpqua Hospital Pharmacy and Therapeutics . Indication(s): Atrial Fibrillation/Flutter with rapid ventricular response (rate reduction) Paroxysmal Supraventricular Tachycardia . Contraindications: Sick Sinus …

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