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https://ehs.research.uiowa.edu/isoflurane-anesthetic-gas-guidelines
Second Choice: Installation of local exhaust over the isoflurane delivery system to address a single source of anesthetic gas, similar to that shown in the photo to the right, or a slot or canopy exhaust for procedures that involve multiple sources of anesthetic gas (e.g., induction box, procedure table, etc.).
https://www.kentscientific.com/products/anesthesia/
Isoflurane and sevoflurane are the currently recommended inhalant anesthetics. Both of these agents require a precision vaporizer for delivery to the animal. Induction of mice or rats with these agents must be conducted in an induction chamber, where concentration is restricted to 5 percent.
https://www.sciencedirect.com/topics/neuroscience/isoflurane
The reduced oxygen requirement is usually sufficient to compensate for any tendency towards impaired oxygen delivery. Thus, isoflurane is preferred over halothane when anesthetizing patients with elevated intracranial pressure.
https://www.kentscientific.com/products/vetflo/
Kent Scientific's VetFlo isoflurane vaporizers are traditional veterinary anesthesia systems that allow for the proper, safe, and effective delivery of inhalant anesthesia for rodents, for use in laboratory settings or as a veterinary anesthesia machine.
https://pattersonscientific.com/products/vaporizer-fill-devices/
Vaporizer fill devices come in two styles: Anti-Spill Funnel/Well fill and Key/Pin Index fill. Fill devices are matched to the fill system on the vaporizer.Available for both Isoflurane and Sevoflurane vaporizers, they are color coded for the specific gas anesthetics: purple for Isoflurane and yellow for Sevoflurane.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698912/
As these simulations demonstrate, targeted delivery achieves a greater degree of bronchodilation compared to continuous delivery for equal within-breath doses of isoflurane. This is due to the fact that during targeted delivery, more drug deposits directly onto the airway surface, as opposed to bypassing this diffusive route and being absorbed directly into the pulmonary circulation.Author: Jarred R. Mondoñedo, John S. McNeil, John S. McNeil, Samir D. Amin, Jacob Herrmann, Brett A. Simon, ...
https://pubchem.ncbi.nlm.nih.gov/compound/isoflurane
Isoflurane is a fluorinated ether with general anesthetic and muscle relaxant activities. Although the exact mechanism of action has not been established, inhaled isoflurane, appears to act on the lipid matrix of the neuronal cell membrane, which results in disruption of neuronal transmission.
https://www.gehealthcare.com/products/anesthesia-delivery/vaporizers-and-cassettes
Deliver with confidence. Anesthesia vaporizers and cassettes from GE Healthcare are developed for delivery accuracy under a wide range of conditions. With the Aladin2 TM cassettes as well as the mechanical Tec TM 6 Plus and Tec 7 Selectatec TM vaporizers, we offer accuracy, ease of use, and low cost of ownership.
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