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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-51502014000300469
Zakzewisk et al. ( 62) evaluated iontophoresis with four types of waves in the reduction of blood pressure in rabbits. Iontophoresis was administered with the pharmaceutical captopril, an angiotensin converting enzyme inhibitor. The frequency of electrical stimulation was 10 Hz – …
https://link.springer.com/chapter/10.1007/978-3-662-53273-7_4
May 05, 2017 · This chapter provides an introduction to iontophoresis, a noninvasive technique that enables the transport of ions into or through biological tissues. The electrotransport mechanisms, the parameters affecting electrically assisted drug delivery, and practical applications of the technique are discussed in the following chapters.Author: Taís Gratieri, Yogeshvar N. Kalia
https://pdfs.semanticscholar.org/9c0d/3bd2c0c321d8b8729cf96c75d8d4b69a64ea.pdf
Key words: Iontophoresis, Penetration, skin, Topical drug delivery, Transdermal drug delivery etc. INTRODUCTION Currently the transdermal route has become one of the most successful and innovative focus for research in drug delivery, with around 40% of the drug candidate being under clinical evaluation related to transdermal or dermal systems.
https://www.researchgate.net/publication/202296606_Advances_in_Iontophoresis_for_Drug_Delivery
Amongst the number of advantages that iontophoretic drug delivery offers over oral methods and injection are avoidance of first pass effect, possibility of externally controlled flux modulation and precise control over drug input besides remaining unaffected by food intake.
https://www.researchgate.net/publication/316728523_Iontophoresis_Basic_Principles
Based on these results and given the known pharmacokinetics, transdermal iontophoresis could achieve therapeutic drug levels for the management of chemotherapy-induced emesis using a reasonably sized (4-6 cm (2)) patch. The first proposals for the use of electric current in drug delivery dare from the mid 18...
https://www.sciencedirect.com/science/article/pii/B9780815520252100046
This chapter details the concepts, principles, and applications of iontophoresis and explores its current standing and potential in the increasingly growing transdermal drug delivery segment. Transdermal drug delivery systems (TDDS) constitute patches that deliver low-molecular-weight molecules such as fentanyl, clonidine, nicotine, scopolamine, and various hormones such as testosterone, estradiol, and the birth control combinations of norelgestromin/ethinyl estradiol.Author: Longsheng Hu, Priya Batheja, Victor Meidan, Bozena B. Michniak-Kohn
http://www.electrotherapy.org/Assets/Downloads/Iontophoresis%202014.pdf
The term iontophoresis is simply defined as ion transfer (ionto = ion; phoresis = transfer). Iontophoresis is used in therapy, but is not exclusive to this arena, and there are applications in medicine, dentistry, lab sciences and physiology.File Size: 661KB
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2852061/
Transdermal iontophoresis has been used for both local and systemic drug delivery. Applications include local delivery of anaesthetics (e.g. lidocaine) 25, steroids and retinoids to treat acne scarring 26, for the relief of palmar and plantar hyperhidrosis 27, and the administration of pilocarpine in the diagnosis of cystic fibrosis 28 – 30.
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