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https://www.neuromodulation.com/pump
In intrathecal drug delivery, pain medications and/or medications used for spasticity are introduced directly to the spinal fluid (intrathecal space) through a drug delivery system comprised of a pump and catheter. The intrathecal space is usually accessed from the lumbar region of the lower back.
https://www.ucsfhealth.org/treatments/intrathecal-drug-delivery
Intrathecal drug delivery is used to treat pain from a variety of conditions, such as chronic back and neck pain, sciatica, chronic abdominal pain, failed back and neck surgery, cancer and reflex sympathetic dystrophy or complex regional pain syndrome.
https://www.webmd.com/pain-management/guide/spinal-drug-delivery-systems
Pain relief through spinal drug delivery systems, also called intrathecal drug delivery systems, involves implanting a small pump or using a catheter that delivers medication directly to the spinal cord, where pain signals travel. In many cases, spinal drug delivery systems are used to treat people who have cancer pain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4227625/
Nov 06, 2014 · Advances in intrathecal analgesia and intrathecal drug delivery systems have allowed for a range of medications to be used in the control of pain and spasticity. This technique allows for reduced medication doses that can decrease the side effects typically associated with oral or parenteral drug delivery.
https://www.sciencedirect.com/science/article/pii/S0169409X20300120
Intrathecal (IT) administration, i.e., the injection of substances directly into cerebrospinal fluid (CSF) that fills the thecal sac, is a potentially powerful drug delivery approach. This route of administration can achieve a high concentration of therapeutic agent within the central nervous system (CNS) while minimizing off-target exposure and associated toxicity [ 1 ].Author: M.J. Fowler, J.D. Cotter, B.E. Knight, E.M. Sevick-Muraca, D.I. Sandberg, D.I. Sandberg, R.W. Sirian...
https://www.asra.com/page/223/intrathecal-dosing-and-medication-selection
The current intrathecal drug delivery systems (IDDS) are approved by the Food and Drug Administration (FDA) for administration of a single agent and there are only 3 FDA approved agents: baclofen for spasticity and morphine and ziconotide for pain.
http://www.sciencepublishinggroup.com/journal/paperinfo?journalid=257&doi=10.11648/j.ijacm.20200801.15
Intrathecal drug delivery systems (IDDS) have been a valuable therapeutic modality in the treatment of intractable chronic pain, typically reserved for cases where conservative pain management has failed.
https://www.fda.gov/medical-devices/safety-communications/use-caution-implanted-pumps-intrathecal-administration-medicines-pain-management-fda-safety
Nov 14, 2018 · Intrathecal delivery of medication with an implanted pump for pain management is often reserved for patients who fail other treatment options.
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