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https://www.assignmentpoint.com/science/medical/intraocular-implants-for-extended-drug-delivery.html
Ocular Implants for Drug Delivery. Advances in materials science, biomedical engineering, and surgical techniques have encouraged the development of a variety of intraocular therapeutic devices. One class of intraocular devices includes implants for drug delivery, designed to improve the ability to deliver therapeutic drug levels into the eye.
https://www.sciencedirect.com/science/article/pii/S0169409X06001645
1. Introduction. The eye is the organ of choice for the practical implantation or injection of a drug delivery system. The intraocular structures are easily (and visually) accessible and, at the same time, it is confined and isolated from the circulation by the inner and outer blood-retinal barriers.Author: J.L. Bourges, C. Bloquel, C. Bloquel, Aurélien Thomas, Aurélien Thomas, F. Froussart, F. Froussart, ...
https://www.ondrugdelivery.com/biodegradable-implants-sustained-intraocular-delivery-small-large-molecules/
Furthermore, rapid crosslinking at physiological temperatures can swiftly entrap drug molecules, thereby reducing high burst release and thus sustaining drug delivery over a longer term. The degree of crosslinking of the implants influences their pore structure, which in …
https://www.ondrugdelivery.com/scalability-micro-intraocular-implants-devices/
Citation: Bibber D, “Scalability of Micro Intraocular Implants and Devices”. ONdrugDelivery Magazine, Issue 63 (Jan 2016), pp 22-24. Donna Bibber discusses some of these micro-intraocular implants and devices and the scalability challenges associated with each, from the perspective of a plastics engineer.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3306122/
Dec 26, 2010 · To overcome the above mentione d limitations, an increasing number of sustained-release drug delivery devices using different mechanisms and containing a variety of agents have been developed to treat uveitis. This article reviews major drug delivery technologies currently in clinical trials or at experimental stages for treatment of uveitis.Author: Nahid Haghjou, Masoud Soheilian, Mohammad Jafar Abdekhodaie
http://new-glaucoma-treatments.com/sustained-drug-delivery-for-glaucoma-treatment-an-update-from-the-american-glaucoma-society-ags-2017-annual-meeting/
Jun 28, 2017 · Intraocular Injectable Implants In addition to placing glaucoma sustained drug delivery implants outside of the eye, it is also possible to inject them into the eye. Such treatments are already available for retinal diseases.
https://www.sciencedirect.com/science/article/abs/pii/S0169409X06001645
Nov 15, 2006 · Various types of implants can be used as slow release devices delivering locally the needed drug for an extended period of time. Thus, multiple periocular or intraocular injections of the drug can be circumvented and secondary complications minimized. The various compositions of polymers fulfilling specific delivery goals are described.Author: J.L. Bourges, C. Bloquel, C. Bloquel, Aurélien Thomas, Aurélien Thomas, F. Froussart, F. Froussart, ...
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1984-82502010000300024
Intraocular implants are controlled drug delivery systems prepared from biodegradable or non-biodegradable polymers. Generally, these are introduced into the vitreous through an incision in the ocular pars plana, which is located posterior to the lens and anterior to the retina. Despite the invasive characteristics of the implantation technique ...
https://www.researchgate.net/publication/7270728_Drug_delivery_from_ocular_implants
Development of intraocular drug delivery systems (DDSs) is urgently required for the treatment of eye diseases, especially in the posterior segment of the eye (the vitreous cavity, retina, and ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4916551/
Mar 30, 2016 · Keywords: Eye diseases, Intraocular drug delivery, Ocular barriers, Ocular pharmacotherapy, Ophthalmic implants, Ocular drug targeting, Ophthalmology, Targeted therapy Introduction In the human eye, like all other mammals, non-image-forming photosensitive ganglion cells within the retina function to receive the light signals and react ...Author: Jaleh Barar, Ayuob Aghanejad, Marziyeh Fathi, Yadollah Omidi
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