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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2604883/
Dec 10, 2008 · Intranasal delivery provides a practical, non-invasive method of bypassing the blood-brain barrier (BBB) to deliver therapeutic agents to the brain and spinal cord. This technology allows drugs that do not cross the BBB to be delivered to the central nervous system within minutes.Author: Leah R Hanson, William H Frey, William H Frey
http://mysticpharmaceuticals.com/delivery-systems/intranasal-delivery-solutions/
Mystic offers patient-centric delivery systems for systemic intranasal, nose-to-brain, ophthalmic, sublingual, dermal and oral delivery. Our delivery platforms and integration services provides a custom optimized delivery system in combination with your drug or biologic to meet your technical product and market requirements.
http://intranasal.net/DeliveryTechniques/default.htm
A second method of intranasal drug delivery is to take a solubilized medication (liquid form) and drip it into the nose a few drops at a time, allowing it to run down onto the nasal mucosa. This can be done using a syringe or in some instances using the packaged form …
http://intranasal.net/Overview/default.htm
Intranasal (IN) medication delivery is simply another option or method to deliver therapeutic medications to the patient’s blood stream to achieve a desired clinical effect. It is a tool in the therapeutic armamentarium just as oral, rectal, sublingual, intramuscular and intravenous delivery methods are also tools to deliver medications.
https://www.thepharmaeducation.com/2020/04/Nasal-Drug-Delivery-System.html
The Pharma Education Network is an interactive platform has been created with the aim to provide information and support to the pharmacy students and pharmaceutical professionals.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761088/
Nov 08, 2012 · However, while intranasal delivery may, in general, produce a favorable side-effect profile as compared to other delivery routes, each drug must be examined for its particular effects on the nasal mucosa, the sense of smell and the immune system as the drug will likely enter not only the CNS but also the nasal associated lymphatics and deep ...Author: Colin D. Chapman, William H. Frey, Suzanne Craft, Lusine Danielyan, Manfred Hallschmid, Helgi B. Sch...
https://www.sciencedirect.com/science/article/pii/S0361923018303678
5.2. Devices to help nasal delivery. The deposition from various nasal devices is typically measured as the amount or percent deposited in defined segments of the nasal cavity. One of the oldest nasal delivery systems is nasal drops (Kublik and Vidgren, 1998).
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