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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4787057/
Trans-dermal insulin delivery eliminates the problems associated with needles and injections and large surface area of the skin makes it a convenient route for insulin delivery. However, the penetration of insulin is halted by the stratum corneum, the outer most layer of the skin.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581917/
The first closed-loop insulin delivery system adopting subcutaneous insulin delivery route has been approved by the US Food and Drug Administration based on a recent pivotal study. Limitations remain with regards to delays in insulin absorption and action inherently linked to the subcutaneous route of …Author: Lia Bally, Hood Thabit, Roman Hovorka
https://www.endocrineweb.com/guides/insulin/insulin-pump-overview
While insulin can be given by self-injection, people who take multiple daily injections of insulin may also consider using an insulin pump. An insulin pump provides continuous delivery of short acting insulin all day long. The insulin pump substitutes the need for long acting insulin.
https://www.medicalnewstoday.com/articles/323760
Nov 21, 2018 · the route of delivery, or whether the insulin requires injection under the skin,into a vein, or into the lungs by inhalation. People most often deliver insulin into the subcutaneous tissue, or the ...
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