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https://lubrizolcdmo.com/wp-content/uploads/2019/10/AAPS-Presentation-on-Microparticles.pdf
Microparticle Advantages • Effective delivery of insoluble actives • Bolus delivery instead slower IV administration • Targeted drug delivery to specific sites • Reduction of dose frequency and toxicity • Ability to maintain drug in amorphous form • Reduction of local side effects • Maintenance of therapeutic plasma concentrations 8
https://www.ncbi.nlm.nih.gov/pubmed/16490579
An open-label, crossover study of the pharmacokinetics of Insoluble Drug Delivery-MicroParticle fenofibrate in combination with atorvastatin, simvastatin, and extended-release niacin in …Author: Ruth Penn, Robert X. Williams, Dilip K. Guha-Ray, William G. Sawyers, Sandra L. Braun, Keith T. Rain...
https://www.nature.com/articles/s41467-020-15128-9
Mar 12, 2020 · Because ELPs consist of VPGXG repeats (Fig. 1a) found in tropoelastin, they are non-toxic and biocompatible, leading to their extensive application in drug delivery and tissue engineering …Author: Stefan Roberts, Vincent Miao, Simone Costa, Joseph Simon, Garrett Kelly, Tejank Shah, Stefan Zausche...
https://www.researchgate.net/publication/216063311_Micro_particles_An_approach_for_betterment_of_drug_delivery_system
throughput screening and in silico three dimensional drug design has yielded drug candidates with low water solubility and thus an inherently low mucosal permeability which makes the development ...
http://www.ijpbs.com/ijpbsadmin/upload/ijpbs_518f888512e54.pdf
drug delivery. Another advantage is that particles in the magnetic fluid interact strongly with each other, which facilitates the delivery of high concentrations of drug to targeted areas.5 Magnetic microspheres can be filled with drugs or radioactive materials to treat a …
https://www.sciencedirect.com/science/article/pii/S131901641400111X
Controlled release drug delivery includes carriers such as polymer-based disks, microparticles, nanoparticles, pellets in which drug gets encapsulated and release at controlled rates for relatively long periods of time. Such kind of systems often show several …Author: Nidhi, Muzamil Rashid, Veerpal Kaur, Supandeep Singh Hallan, Saurabh Sharma, Neeraj Mishra
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4923250/
Jun 28, 2016 · Any water insoluble material can be used as the microparticle matrix to produce the desired drug release profiles, and microparticles are recovered from the readily soluble hydrogel templates. The technology allows for precise control of the size and shape of template wells in every dimension so that microparticles with a narrow size distribution can be produced (Lu et al., 2014 ; …Author: Felicity Y. Han, Kristofer J. Thurecht, Andrew K. Whittaker, Maree T. Smith
https://www.researchgate.net/publication/260273163_Microparticulate_drug_delivery_system_a_review
Microspheres/microparticles constitute an important part of this particulate drug delivery system by virtue of their small size and efficient carrier characteristics. These delivery systems offer...
https://www.sciencedirect.com/science/article/abs/pii/S0149291805003164
The objective of this study was to determinethe effect of administering a single dose of atorvastatin, simvastatin, or extended-release (ER) niacin on the pharmacokinetics and safety of a single dose of fenofibrate Insoluble Drug Delivery®-MicroParticle (IDD-P).Author: Ruth Penn, Robert X. Williams, Dilip K. Guha-Ray, William G. Sawyers, Sandra L. Braun, Keith T. Rain...
http://sphinxsai.com/Vol.3No.3/pharm/pdf/PT=05(1242-1254)JS11.pdf
Microparticulate drug delivery system is one of the processes to provide the sustained & controlled delivery of drug to long periods of time. They are small particles of solids or small droplets of liquids surrounded by walls of natural & synthetic polymer films of varying thickness & degree of permeability acting as a release rate controlling substance & have a diameter upto the range of 0.1µm-200µm [1]. …
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