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https://www.sciencedirect.com/science/article/pii/S1471490617301898
Encapsulation of vaccine cargo into polymeric or lipid particles is a continuing theme in the vaccine field to improve co-delivery of antigen and adjuvant, or achieve desirable delivery kinetics through controlled cargo release (Figure 2B). The particulate nature of material platforms also generally enhances uptake by APCs 29, 30, 31.Author: Michelle L. Bookstaver, Shannon J. Tsai, Jonathan S. Bromberg, Christopher M. Jewell
https://www.sciencedirect.com/science/article/pii/S0958166916300581
One approach to improve vaccine thermal stability is to formulate the constituents with the addition of stabilizing agents. One study found that encapsulation of the measles, mumps, and rubella (MMR) vaccine in silk films vastly improved the retention of potency following storage at elevated temperatures .Author: Andrew B Hill, Christopher Kilgore, Margaret McGlynn, Charles H Jones
https://albumedix.com/products/recombumin/vaccine-stabilization/
Maintaining vaccine stability. Vaccines continue to be an important field of pharmaceutical research, offering valuable therapeutic and prophylactic patient benefits. Like other biologics, vaccines are susceptible to environmental stress, such as temperature changes and physical strain.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4743593/
Jul 01, 2014 · To ensure the optimal potency of vaccines, careful attention is needed in handling practices at all levels of the cold chain. These include storage and transport of vaccines from the manufacturer through the primary vaccine store down to the end user at the health facility and further down at the outreach sites.Author: Umit Kartoglu, Julie Milstien
https://www.researchgate.net/publication/330155430_Stability_of_Vaccines
However, results at a 10% non-inferiority margin, the comparable GMC increases and vaccine's stability demonstrated in the preliminary phase indicate that CTC can be an alternative strategy for TT ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816528/
Synthetic DNA Vaccines: Improved Vaccine Potency by Electroporation and Co-Delivered Genetic Adjuvants. ... Delivery of DNA vaccine with in vivo electroporation enhances cellular immune responses. A DNA vaccine encoding HIV-1 consensus immunogens was injected intramuscularly with or without EP into rhesus macaques.
https://www.ars.usda.gov/gfra/GFRA%20Scientific%20Meeting%202017/day2/8%20-%20Vaccine%20Delivery%20Routes%20and%20Adjuvants/8-1.%20Improving%20FMDV%20potency%20by%20modification%20of%20vaccination%20protocols_Fayna%20Diaz%20San%20Segundo.pdf
Improving FMD vaccine potency by modification of vaccination protocols Fayna Diaz‐San Segundo, Elizabeth Ramirez‐Medina, Gisselle Medina, Luis L. Rodriguez and Teresa de los Santos Plum Island Animal Disease Center.
https://path.azureedge.net/media/documents/TS_vaccine_stability_table.pdf
Summary of stability data . for licensed vaccines. Produced by Working in Tandem, Ltd., for the PATH Vaccine and Pharmaceutical Technologies Group. This summary was advanced with funds provided by the Bill & Melinda Gates Foundation. through the Thermostable Vaccines for Developing Countries project at PATH. PATH. CONTACT. Debra Kristensen, MBAFile Size: 1MB
https://www.researchgate.net/publication/241704090_Improving_Vaccine_Potency_Through_Intercellular_Spreading_and_Enhanced_MHC_Class_I_Presentation_of_Antigen1
Improving Vaccine Potency Through Intercellular Spreading and Enhanced MHC Class I Presentation of Antigen1 Article in The Journal of Immunology 166(9):5733-5740 · May 2001 with 19 Reads
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