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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3576846/
The simplest miniaturized implantable drug-delivery systems feature a reservoir with a membrane that controls the onset or rate of drug administration. Reservoir-based drug-delivery systems may require additional energy to overcome the diffusion limited transport of drug in …Author: Ellis Meng, Tuan Hoang
https://www.sciencedirect.com/science/article/pii/B9780081025482000056
Implantable drug delivery systems provide extended release of a drug for the desired duration, usually over timespans of months and years. A broad range of materials are currently in use for the fabrication of implants, both nondegradable and biodegradable, the choice of which will depend on the drug being delivered, the type and length of drug release required, and whether or not the device ...Author: Ian Major, Sarah Lastakchi, Maurice Dalton, Christopher McConville
https://promedmolding.com/implantable-drug-delivery-devices-overview/
Dec 18, 2017 · As with all implantable devices, key materials considerations for use in drug delivery include biocompatibility, stability and durability (except in the case of biodegradable drug delivery systems), and the ability of the material to control release of the active pharmaceutical ingredient (API).
https://www.researchgate.net/publication/319327771_Implantable_drug_delivery_systems_An_Overview
Implantable drug delivery systems offer physicians the choice of precision delivery, either locally or into systemic circulation, while guaranteeing optimal dosing over the course of treatment.The ...
https://www.sciencedirect.com/science/article/pii/B9780128136652000132
The concept of implantable drug delivery systems (IDDSs) in modern medicine may be traced to Deansby and Parkes who, in 1938, subcutaneously (SC) implanted compressed pellets of crystalline estrone to study their effect upon castrated male chickens (Kleiner et al., 2014).Folkman and Long pioneered implantable formulations, with drug release rates controlled by a polymeric membrane, in the 1960s.Author: Anoop Kumar, Jonathan Pillai
https://www.pharmatutor.org/articles/review-implantable-drug-delivery-system
Therefore, drug delivery systems were developed to optimize the therapeutic properties of drug products and render them more safe, effective, and reliable. In comparison with many of the other drug delivery systems, implantable pumps and implants for variable rate delivery are at a crude stage of development.
https://www.aao.org/eyenet/article/promise-of-implantable-drug-delivery-systems
Still in its youth, implantable drug delivery is nevertheless beginning to offer up a few pearls of wisdom. Location, location, location. Where an implant resides in the …
https://www.slideshare.net/pareshbharodiya/implantable-drug-delivery-system
May 13, 2010 · various approaches to design implantable drug delivery system. various approaches to design implantable drug delivery system. ... Implantable drug delivery systeman introduction <br />Implantable drug delivery systems are placed completely under the skin — usually in a convenient but inconspicuous location. The patient is aware of only a ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4441594/
Implantable drug delivery systems (DDS) provide a platform for sustained release of therapeutic agents over a period of weeks to months and sometimes years. Such strategies are typically used clinically to increase patient compliance by replacing frequent ...Author: Haoyan Zhou, Christopher Hernandez, Monika Goss, Anna Gawlik, Agata A. Exner
http://cirtecmed.com/product-categories/implantable-drug-delivery/
Implantable Drug Delivery Precision Drug Therapies Often designed as active implants, these devices are increasingly helping to treat chronic pain, cancer, diabetes and other conditions. Typical designs comprise a reservoir for medication, a battery-powered pump programmed to release the medication at prescribed dosages and intervals and a catheter that serves as the delivery channel. The …
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