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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340983/
Dec 11, 2013 · However, ibuprofen shows the poor gastrointestinal absorption because of the low solubility or dissolution rate to water (10-12). Therefore, the clinical use of ibuprofen was limited. Recently, increasing attention has focused on transdermal delivery of ibuprofen. Various dermal dosage forms such as patch and gels has been reported.Author: Liandong Hu, Qiaofeng Hu, Jianxue Yang
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5629190/
Oct 05, 2017 · Transdermal ibuprofen delivery has been shown to be superior to placebo and comparable to oral ibuprofen in terms of efficacy, while also leading to fewer or less serious side effects. Topical ibuprofen may also be more cost-effective in the long term due to decreased rates of complications and hospitalization.Author: Martin Anthony Christopher Manoukian, Christopher William Migdal, Amode Ravindra Tembhekar, Jerad Al...
https://www.medherant.co.uk/
Medherant is creating a sustainable, next-generation transdermal drug delivery patch company that creates value for patients, partners and investors.
https://www.cnet.com/news/researchers-develop-ibuprofen-patch-that-works-through-the-skin/
Dec 08, 2015 · New ibuprofen skin patch to deliver 12 hours of pain relief. Where does it hurt? Newly developed patch technology could change the way drugs are delivered through the skin.
https://www.medherant.co.uk/our-products/ibuprofen-tepi-patch
Medherant has completed Phase I clinical trials with its Ibuprofen TEPI Patch ® and is seeking a partner to complete the development programme and commercialise the product. The worldwide topical pain relief market is growing and was worth $7,481m in 2017*.
https://www.newsmax.com/Health/Health-News/ibuprofen-patch-transdermal-pain/2016/02/22/id/715511/
An ibuprofen patch that delivers the painkiller directly through the skin to the site of pain, at a consistent dose for up to 24 hours, has been developed by U.K. researchers. Scientists at the University of Warwick and spin-off company Medherant say their TEPI patch …
https://www.sciencedirect.com/science/article/pii/S0167732218356216
The aim of this study was to explore the feasibility of transdermal delivery of ibuprofen using ionic liquid technology. Ibuprofen, a non-steroidal anti-inflammatory drug, was transformed into nine ionic liquids using aromatic, tetraalkylammonium and tetraalkylphosphonium cationic counterions.Author: Hao Wu, Zhaizhu Deng, Bijiang Zhou, Minghui Qi, Minghuang Hong, Guobin Ren
https://www.sciencedirect.com/science/article/pii/S0168365997001533
The formation of eutectic systems between ibuprofen (ibu) and seven terpene skin penetration enhancers was studied and, by using the eutectic systems as donors, the effects of melting point depression of the delivery system on transdermal delivery were investigated.Author: Paul W Stott, Adrian C Williams, Brian W Barry
http://www.bioline.org.br/pdf?pr10042
Development and Evaluation of Ibuprofen Transdermal Gel Formulations Bazigha K Abdul Rasool 1*, Eman F Abu-Gharbieh 1, Sahar A Fahmy 2, Heyam S Saad 1 and Saeed A Khan 1 1Dubai Pharmacy College, Dubai, UAE, 2Helwan University, Helwan, Egypt Abstract Purpose: To develop an ibuprofen transdermal gel with a capability for both topical and systemic ...
https://www.medicalnewstoday.com/articles/303838
Dec 09, 2015 · New ibuprofen patch delivers drug without risks posed by oral dose Written by Marie Ellis on December 9, 2015 Ibuprofen is used by many people to …
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