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https://www.covid19treatmentguidelines.nih.gov/management/critical-care/oxygenation-and-ventilation/
The optimal oxygen saturation (SpO 2) in adults with COVID-19 who are receiving supplemental oxygen is uncertain. However, a target SpO 2 of 92% to 96% seems logical, considering that indirect evidence from patients without COVID-19 suggests that an SpO 2 <92% or >96% may be harmful.
https://www.ncbi.nlm.nih.gov/books/NBK430743/
100% oxygen can be tolerated at sea level for about 24-48 hours without any severe tissue damage. Lengthy exposures produce definite tissue injury.
https://clinicaltrials.gov/ct2/show/NCT00001464
This study is designed to evaluate the effects of oxygen therapy at 100% and 40% for 12 18 hours on the lungs of normal volunteers. Results of this study will help to determine if levels of oxygen therapy currently accepted as being "safe" may actually be damaging to the lungs.
https://www.medicinenet.com/what_are_blood_oxygen_levels/article.htm
Blood oxygen levels below 90% are considered low (hypoxemia). Hyperoxemia is generally detected using ABG testing and is defined as blood oxygen levels above 120 mmHg. This is mostly seen in hospitals when patients are exposed to high pressures of supplemental oxygen for prolonged periods (3 to more than 10 hours).
https://www.simple-remedies.com/health-questions/high-oxygen-levels-in-blood-causes.html
High levels of oxygen in the blood occur as a result of breathing in concentrated oxygen. It is considered a grave condition and can result in cell damage and cell death, chiefly in the eyes, central nervous system, and lungs. Those who could develop this condition are – scuba divers, given that, they are subjected to high atmospheric pressure.
https://www.inogen.com/blog/safe-oxygen-levels/
An oxygen level below 88% can be dangerous for any period of time. An oxygen level below 85% warrants a trip to the hospital. Keep in mind that an oxygen level 80 % and lower puts your vital organs in danger, so it is important to keep a blood oxygen level chart handy so you know what levels require immediate treatment.
https://upstatehomecare.com/assets/approximate-oxygen-tank-duration-times.pdf
Patient Education # 0011 Rev: 3/18. Oxygen Flow Rate (LPM).5 1 1.5 2 2.5 3 3.5 4 5 6 . TANK SIZES. Approximate Duration Time. E . 22.7 11.3 7.5 5.6 4.5 3.7 3.2 2.8 2.2 1.8
https://www.oxygenconcentratorstore.com/help-center/how-high-can-your-oxygen-level-go-on-an-oxygen-concentrator/
The highest flow oxygen concentrators output oxygen flow at 10 liters per minute. The Respironics Millennium M10, Invacare Platinum 10, and the AirSep Intensity 10 are three home oxygen concentrator machines that deliver this highest oxygen level. These units allow safe oxygen use without the refill requirements or flammability of old-fashioned oxygen tanks.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1114067/
As oxygen is 21% of dry air, the inspired oxygen pressure is 0.21×(100−6.3)=19.6 kPa at sea level. Atmospheric pressure and inspired oxygen pressure fall roughly linearly with altitude to be 50% of the sea level value at 5500 m and only 30% of the sea level value at …
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