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https://www.ncbi.nlm.nih.gov/books/NBK557820/
The symptoms usually begin 2 hours from the administration of the antibiotic and resolve within 24 hours.
https://www.sciencedirect.com/topics/immunology-and-microbiology/herxheimer-reaction
The reaction begins within 2 hours of treatment, peaks at approximately 8 hours, and disappears in 24 to 36 hours. The cause of Jarisch-Herxheimer reaction is unknown [435], although release of T. pallidum membrane lipoproteins that stimulate proinflammatory cytokines likely explains this clinical phenomenon [436].
https://candidaspecialists.com/herxheimer-reaction-herxing/
Herxheimer reaction symptoms can last anywhere between a few hours to a few days, sometimes up to a week, with most people feel a relief in less than 24 hours. Herxheimer reaction symptoms in many cases are similar to flu-like symptoms and may include:
https://lymerecoveryclinic.com/foolproof-ways-to-stop-a-herxheimer-reaction/
The typical Herxheimer reaction or “Herx” lasts a few hours to a few days depending on the intensity of treatment and the body’s inflammation response. Many patients also experience a brief period of feeling better shortly after the herxing has subsided.
Herxheimer 11 hours ago. 0 . Alcohol Withdrawal Syndrome Overview. Read More » ...
https://madisonarealymesupportgroup.com/2021/03/02/what-is-a-herxheimer-reaction-and-what-can-i-do-about-it/
Typically, symptoms develop within a couple of hours to several days after treatment. However, depending on the location of the bacteria, symptoms may develop later. Because of the sudden worsening of symptoms, it is common for patients to feel that the severity of their condition has increased due to the treatment.
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