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https://www.sciencedirect.com/science/article/pii/S0169409X20300107
6. Smart drug delivery systems (SDDS) in hyperthermia 6.1. Introduction to smart drug delivery systems. Smart Drug Delivery Systems (SDDS) can be defined as structures which incorporate chemotherapeutics, or agents which have an activity that benefits tumor therapy, and combine that with an additional functionality in order to improve treatment ...Author: A.L.B. Seynhaeve, M. Amin, D. Haemmerich, G.C. van Rhoon, T.L.M. ten Hagen
https://www.sciencedirect.com/science/article/pii/S0169409X20300041
Overall, copious photothermal agents based on conjugated polymers have been explored and the field continues to be developed due to the low toxicity of their nanoparticles in the absence of NIR stimulation and the potential to serve as imaging, hyperthermia and drug delivery vehicles.Author: Santu Sarkar, Nicole Levi-Polyachenko
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3138885/
Aug 14, 2011 · The review also focuses for the first time on the application of core-shell type magnetic nanomaterials for hyperthermia-based therapy and controlled drug delivery. For the purpose of this review, core-shell MNPs are those that have a core and a shell made up of different metals or oxides.Author: Challa S.S.R. Kumar, Faruq Mohammad, Faruq Mohammad
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4840378/
Apr 22, 2016 · Fe(Salen) nanoparticles should rapidly heat up in an alternating magnetic field (AMF), and we hypothesized that these single-drug nanoparticles would be effective for combined hyperthermia-chemotherapy. Conventional hyperthermic particles are usually made of iron oxide, and thus cannot exhibit anti-cancer activity in the absence of an AMF.Author: Itaru Sato, Masanari Umemura, Kenji Mitsudo, Hidenobu Fukumura, Jeong Hwan Kim, Yujiro Hoshino, Hide...
https://www.nature.com/articles/s41551-018-0297-8
Sep 11, 2018 · A clinical study shows the feasibility and safety of the intratumoral release of an anticancer drug encapsulated in thermosensitive liposomes by …Author: Kullervo Hynynen
https://pubs.rsna.org/doi/10.1148/radiol.2018181445
Feasibility was confirmed on the basis of the negligible mean difference between model-predicted and actual focused ultrasound powers (−0.1 W) required to achieve hyperthermia-mediated drug delivery, whereas safety was confirmed on the basis of a lack of focused ultrasound–related adverse effects.Author: Michael D. Gray, Paul C. Lyon, Christophoros Mannaris, Lisa K. Folkes, Michael Stratford, Leticia Ca...
https://www.thno.org/v07p2718.pdf
combining mild hyperthermia (HT) with lyso -thermosensitive liposomal doxorubicin (LTSL -DOX) has led to improved drug delivery and potent antitumor effects in pre -clinical studies. The ultimate patient benefit from these treatments can only be realized when robust methods of HT can be achieved clinically.
https://www.thno.org/v07p2718.htm
Focused Ultrasound Hyperthermia Mediated Drug Delivery Using Thermosensitive Liposomes and Visualized With in vivo Two-Photon Microscopy . Marc A. Santos 1, 2 , David E. Goertz 1, 2, Kullervo Hynynen 1, 2, 3. 1. Physical Sciences Platform, Sunnybrook Research Institute, Toronto, ON, Canada; 2.
https://www.mdpi.com/2072-6694/11/10/1512
Tumor drug distribution and concentration are important factors for effective tumor treatment. A promising method to enhance the distribution and the concentration of the drug in the tumor is to encapsulate the drug in a temperature sensitive liposome. ... Tumor Drug Distribution after Local Drug Delivery by Hyperthermia, In Vivo . by Helena C ...Author: Helena C. Besse, Angelique D. Barten-Van Rijbroek, Kim M.G. van der Wurff-Jacobs, Clemens Bos, Chrit...
https://celsion.com/wp-content/uploads/2016/06/Landon-Nanomedicine-Jl-2011.pdf
40 The Open Nanomedicine Journal, 2011, Volume 3 Landon et al. Hyperthermia treatment is known to increase tumor blood flow and vascular permeability and may therefore in-crease drug delivery …
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