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https://pubs.acs.org/doi/abs/10.1021/bm300966d
Biodegradable hyperbranched polyglycerols (dHPGs) were synthesized through oxyanionic initiating hybrid polymerization of glycerol and glycidyl methacrylate. Due to the introduction of ester linkages into the hyperbranched polyglycerol backbone, dHPGs showed good biodegradability and low cytotoxicity. Benefiting from the existence of terminal hydroxyls and methacryloyl groups, both the ...Author: Mei Hu, Mingsheng Chen, Guolin Li, Yan Pang, Dali Wang, Jieli Wu, Feng Qiu, Xinyuan Zhu, Jian Sun
https://pubs.acs.org/doi/10.1021/bm025738i
A novel approach to hyperbranched polymers is presented in this work. Hyperbranched polyesters with a large amount of terminal hydroxyl groups are prepared by a one-pot synthesis from commercially available AB-type and CDn-type monomers (n ≥ 2). In this paper, Michael addition of diethanolamine (CD2) or N-methyl-d-glucamine (CD5) to methyl acrylate (AB) generates dominantly ADn-type ...Author: Chao Gao, Yimin Xu, Deyue Yan, Wei Chen
https://www.hindawi.com/journals/jnt/2017/7607658/
Therefore, for the purposes of cell sorting, medical diagnosis and controlled drug delivery, the strategy for the synthesis of magnetic cobalt nanoparticles is based on the use of non-toxic, biosimilar and biodegradable hyperbranched polymers and dendrimers. Such compounds include hyperbranched polyester polyols (HBPO) of various generations.Author: O. I. Medvedeva, S. S. Kambulova, O. V. Bondar, A. R. Gataulina, N. A. Ulakhovich, A. V. Gerasimov, ...
https://www.sciencedirect.com/science/article/pii/S0014305716303810
These core-shell biodegradable hyperbranched polyesters have been used as drug delivery systems (DDS) so as to enhance the solubility of highly hydrophobic molecules. Pyrene has been studied as a model to evaluate the potential drug transport capability and the critical micelle concentration (CMC) of these amphiphilic systems.Author: Stefano Stefani, Sunil K. Sharma, Rainer Haag, Paul Servin
https://link.springer.com/article/10.1007/s40199-020-00328-x
Jan 31, 2020 · Rod-like mesoporous silica nanoparticles with pH-responsive amphiphilic hyperbranched polyester shells were prepared for doxorubicin (DOX) delivery. First, rod-shaped mesoporous silica nanoparticles (MSNs) were obtained, then hydrophobic hyperbranched polyester Boltorn H40 (H40) was grafted on their surface. The H40 coated MSNs were next treated with amine-functionalized …Author: Reza Bafkary, Shirin Ahmadi, Faeze Fayazi, Mehdi Karimi, Yousef Fatahi, Seyed Mostafa Ebrahimi, Fate...
https://www.researchgate.net/publication/321273539_A_hyperbranched_amphiphilic_acetal_polymer_for_pH-sensitive_drug_delivery
Nanoparticles are appealing drug delivery systems since they promise prolonged circulation time and predictable release behaviors. The current work reports a novel hyperbranched amphiphilic block ...
https://www.sciencedirect.com/science/article/pii/S0168365920301103
Drug delivery systems have been developed considering various types of materials including mesoporous silica nanoparticles [], lipids [2,3], and polymers [, , ].Inorganic nanoparticles have gained interest due to their optical, magnetic and plasmonic properties, but show limitations in clinic due to their cytotoxicity and limited drug loading [7,8].Author: Alireza Kavand, Nicolas Anton, Thierry Vandamme, Christophe A. Serra, Delphine Chan-Seng
https://www.researchgate.net/publication/5365132_A_Novel_Micellar_PEGylated_Hyperbranched_Polyester_as_a_Prospective_Drug_Delivery_System_for_Paclitaxel
A Novel Micellar PEGylated Hyperbranched Polyester as a Prospective Drug Delivery System for Paclitaxel Article in Macromolecular Bioscience 8(9):871-81 · September 2008 with 99 Reads
https://www.onlinelibrary.wiley.com/doi/pdf/10.1002/mabi.200800015
A hyperbranched aliphatic polyester has been functionalized with PEG chains to afford a novel water‐soluble BH40‐PEG polymer which exhibits unimolecular micellar properties, and is therefore appropriate for application as a drug‐delivery system.Author: Christina Kontoyianni, Zili Sideratou, Theodossis Theodossiou, Leto-Aikaterini Tziveleka, Dimitris T...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3653976/
May 13, 2013 · Hyperbranched polyester hydrogels were made by crosslinking hyperbranched polyester macromers with sustained drug release characteristic. Formation of covalently crosslinked hyperbranched polymeric network results in mechanically tough …Author: Hongbin Zhang, Alpesh Patel, Akhilesh K. Gaharwar, Silvia M. Mihaila, Giorgio Iviglia, Shilpaa Mukun...
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