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https://www.researchgate.net/publication/288392105_Hydrophilic_Matrices_for_Oral_Control_Drug_Delivery
Oral controlled drug delivery has gathered tremendous attention over the years due to its many advantages over conventional dosage forms. Polymer-based matrices have become an …
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648939/
Nov 04, 2012 · Viscosity can therefore affect the extent of drug release from hydrophilic matrices. Rahman et al. (2011) explored viscosity grades of HPMC matrix systems as oral controlled release drug delivery systems using a non-steroidal anti-inflammatory drug, diclofenac sodium (Fig. 7). All viscosities of HPMC were used which included K100M, K15M, K4M ...Author: Ali Nokhodchi, Shaista Raja, Pryia Patel, Kofi Asare-Addo
https://www.sciencedirect.com/science/article/pii/S0141813020328142
This study aims to explore the potential of gum extracted from okra fruit (Hibiscus esculentus) in developing hydrophilic matrices for controlled drug release applications, including determination of its percolation threshold.Flurbiprofen (poorly soluble), theophylline (sparingly soluble) and metformin (freely soluble) were employed as model drugs and incorporated using direct compression into ...
https://link.springer.com/article/10.1023/A:1026455822595
Oct 01, 2000 · Conclusions. The practical benefit of this work is an improved design model that can be used to predict accurately the required composition and dimensions of drug-loaded hydrophilic matrices in order to achieve desired release profiles, thus facilitating the development of …Author: J. Siepmann, Nicholas Peppas
https://www.sciencedirect.com/science/article/pii/S037851730500846X
Mar 27, 2006 · The hydrophilic matrices are one of the most used controlled delivery systems in the world, due to the simple technology and low cost. Its study is a difficult task due to its complex and disordered structure. A number of publications have reported studies about the mechanisms of drug release from hydrophilic matrices.Author: Antonia Miranda, Mónica Millán, Isidoro Caraballo
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