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https://www.sciencedirect.com/science/article/pii/S0032386108000487
Indeed, the benefits of hydrogels for drug delivery may be largely pharmacokinetic – specifically that a depot formulation is created from which drugs slowly elute, maintaining a high local concentration of drug in the surrounding tissues over an extended period, although they can also be used for systemic delivery.Author: Todd R. Hoare, Daniel S. Kohane
https://www.semanticscholar.org/paper/HYDROGELS-IN-TOPICAL-DRUG-DELIVERY-%E2%80%93-A-REVIEW-Silna-Krishnakumar/56ea8237bdfea2326980ffd20c55a70bfaa0b499
This review disclose the convenience of hydrogel as a topical drug delivery system anywhere in the body by the route of ophthalmic, rectal, vaginal and skin. Delivery of drug through topical route represents a most convenient and novel approach.
https://pubs.acs.org/doi/10.1021/acs.molpharmaceut.9b01020
A hydrogel drug carrier can cause less severe side effects than systemic chemotherapy and can achieve sustained delivery of a drug at tumor sites. In addition, hydrogels have excellent biocompatibility and biodegradability and lower toxicity than nanoparticle carriers.Author: Zhaoyi Sun, Chengjun Song, Chao Wang, Yiqiao Hu, Jinhui Wu
https://www.researchgate.net/publication/224319682_As_A_Review_on_Hydrogels_as_Drug_Delivery_in_the_Pharmaceutical_Field
Hydrogels that are responsive to specific molecules, such as glucose or antigens, can be used as biosensors as well as drug delivery systems. New synthetic methods have …
https://journals.sagepub.com/doi/10.1177/228080000700500301
Sep 01, 2007 · This hydrogel property can be utilized for drug delivery applications. A literature search suggests that current research related to stimuli responsive drug delivery systems deals with temperature sensitive, pH sensitive, glucose sensitive and bio-molecule sensitive hydrogels.Author: R.V. Kulkarni, Sa. Biswanath
https://www.researchgate.net/publication/285964581_Hydrogels_as_a_drug_delivery_system_and_applications_A_review
This review will emphasize on the various aspects of the hydrogels. Hydrogels that undergo swelling changes in response to specific biomolecules have become increasingly important because of their...
https://www.nature.com/articles/natrevmats201671
Oct 18, 2016 · In this Review, we cover multiscale mechanisms underlying the design of hydrogel drug delivery systems, focusing on physical and chemical properties of the hydrogel network and the hydrogel–drug...Author: Jianyu Li, David J. Mooney
https://pubs.acs.org/doi/10.1021/cr200157d
In-situ mineralization of calcium carbonate in pectin based edible hydrogel for the delivery of protein at colon. Journal of Drug Delivery Science and Technology 2019, 53, 101137. DOI: 10.1016/j.jddst.2019.101137. Mehmet Can, Ramesh S. Ayyala, Nurettin Sahiner.Author: Tina Vermonden, Roberta Censi, Wim E. Hennink
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells. Owing to their ...Author: Jianyu Li, David J. Mooney
https://www.sciencedirect.com/science/article/pii/S0169409X12002700
1. Introduction. Since the pioneering work of Wichterle and Lim in 1960 on crosslinked HEMA hydrogels , and because of their hydrophilic character and potential to be biocompatible, hydrogels have been of great interest to biomaterial scientists for many years , , , , , , , .The important and influential work of Lim and Sun in 1980 demonstrated the successful application of calcium alginate ...Author: Allan S Hoffman
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