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http://isn.ucsd.edu/courses/beng221/problems/2012/BENG221_Project%20-%20Wei%20Kim%20Kim%20Limsakul.pdf
delivery system comprises a drug core entrapped in a spherical, cylindrical, and slab-like-shaped reservoir, which is in turn encapsulated within a hydrogel membrane. In order to ensure drug delivery at a constant rate, the drug can be concentrated in the center of the device such that the
http://e-space.mmu.ac.uk/615529/2/Internal-Report.pdf
Hydrogel Drug Delivery: Difiusion Models Frank Bierbrauer School of Mathematics and Applied Statistics, University of Wollongong NSW, 2522, Australia 1 Introduction The delivery of drugs for pharmaceutical and medical applications is usually achieved through a variety of drug delivery systems such as injections, tablets and sprays.
https://www.semanticscholar.org/paper/Hydrogel-Drug-Delivery%3A-Diffusion-Models-Bierbrauer/69938fd5914a73f1eadb191445dfb4ab55772d78
The delivery of drugs for pharmaceutical and medical applications is usually achieved through a variety of drug delivery systems such as injections, tablets and sprays. These systems must deliver the correct dose of the drug in an efficient manner, that is: a controlled delivery which maintains the optimal concentration within the bloodstream in order to be therapeutically effective for ...
http://vip.gatech.edu/wiki/images/b/bb/Solute_diffusion_within_hydrogels.pdf
the delivery of bioactive agents to the body4-6 and prosthetic applications.3,4 The one feature of hydrogels that all these applications capitalize upon is the ability of the hydrogel to restrict the diffusive movement of a solute. It is therefore important to have an understand-ing of the parameters governing solute diffusion within
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846103/
There have been several nicely written reviews on mathematical modeling for bioerodible polymeric delivery systems , dissolution controlled drug delivery systems , microsphere delivery systems and hydrogel networks . In general, diffusion, erosion, and degradation are the most important mechanisms for solute transport from polymeric matrices.Author: Yao Fu, Weiyuan John Kao
https://www.sciencedirect.com/science/article/pii/S0928493111001020
Jul 20, 2011 · The current work provides important implications for controllable hydrogel drug delivery. The swelling-diffusion measurements suggest that the drug delivery processes of PNIPA based hydrogels can be controlled by both the hydrophilic comonomer …Author: G. Fu, W.O. Soboyejo
https://pubs.acs.org/doi/abs/10.1021/ma980765f
Solute diffusion in hydrogels is important in many biotechnology fields. Solute behavior in hydrogels has been explained in terms of reduction in hydrogel free volume, enhanced hydrodynamic drag on the solute, increased path length due to obstruction, and a combination of hydrodynamic drag and obstruction effects. In this article the various mathematical models derived to explain and predict ...Author: Brian Amsden
https://pubs.acs.org/doi/abs/10.1021/mp500563n
Dec 11, 2014 · In this work the behavior of hydrogel-based matrices, the most widespread systems for oral controlled release of pharmaceuticals, has been mathematically described. In addition, the calculations of the model have been validated against a rich set of experimental data obtained working with tablets made of hydroxypropyl methylcellulose (a hydrogel) and theophylline (a model drug).Author: Diego Caccavo, Sara Cascone, Gaetano Lamberti, Anna Angela Barba
https://www.researchgate.net/publication/224319682_As_A_Review_on_Hydrogels_as_Drug_Delivery_in_the_Pharmaceutical_Field
Hydrogel is a network of polymer chains that are water-insoluble, sometimes found as a colloidal gel in which water is the dispersion medium. Hydrogels are crosslinked polymer networks that absorb ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898614/
Hydrogel delivery systems can leverage therapeutically beneficial outcomes of drug delivery and have found clinical use. Hydrogels can provide spatial and temporal control over the release of various therapeutic agents, including small-molecule drugs, macromolecular drugs and cells. Owing to their ...Author: Jianyu Li, David J. Mooney
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