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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3120056/
HPV pseudovirions for the delivery of DNA vaccines. HPV pseudovirions have also been used to deliver DNA vaccines. The major obstacle to DNA vaccination is the delivery of the DNA into cells. Hence, HPV pseudovirions to package DNA vaccine present many potential advantages compared with naked DNA and other routes of administration.Author: Barbara Ma, Richard S Roden, Chien-Fu Hung, Tzyy Choou Wu
https://www.researchgate.net/publication/51254220_HPV_pseudovirions_as_DNA_delivery_vehicles
We have examined non-replicative human papillomavirus (HPV) pseudovirions as an approach in the delivery of naked DNA vaccines without safety concerns associated with live viral vectors.
https://www.ncbi.nlm.nih.gov/pubmed/21709779
HPV pseudovirions as DNA delivery vehicles. Ma B, Roden RB, Hung CF, Wu TC. "The ability of HPV pseudovirions to efficiently deliver DNA into cells suggests several potential applications in basic biology, including the characterization of virion biology and measurement of protective neutralizing antibody titers in vitro and in vivo, as well as ...Author: Barbara Ma, Richard S Roden, Chien-Fu Hung, Tzyy Choou Wu
http://europepmc.org/articles/PMC3120056
HPV pseudovirions for the delivery of DNA vaccines. HPV pseudovirions have also been used to deliver DNA vaccines. The major obstacle to DNA vaccination is the delivery of the DNA into cells. Hence, HPV pseudovirions to package DNA vaccine present many potential advantages compared with naked DNA and other routes of administration.
https://www.future-science.com/doi/10.4155/tde.11.28
Therapeutic Delivery Vol. 2, No. 4 Special Focus: Gene Delivery - Editorial. HPV pseudovirions as DNA delivery vehicles. Barbara Ma, Richard BS Roden, Chien-Fu Hung &Author: Barbara Ma, Richard S Roden, Chien-Fu Hung, Tzyy Choou Wu
http://www.nature.com/articles/srep20431
Feb 08, 2016 · This demonstrates a significant potential for HPV-derived PsVs to be used as DNA delivery vehicles, whether for use as vaccines or potentially for …Author: Renate L Lamprecht, Paul Kennedy, Suzanne M Huddy, Susanne Bethke, Megan Hendrikse, Inga I Hitzeroth...
https://cellandbioscience.biomedcentral.com/articles/10.1186/2045-3701-1-26
Jul 28, 2011 · Background. Human papillomavirus (HPV) pseudovirions have recently been shown to deliver DNA efficiently in vivo, resulting in the priming of antigen-specific CD8+ T cells in vaccinated mice.In the current study, we compare the different preparation methods for the generation of HPV pseudovirions for their ability to efficiently infect cells.Author: Shiwen Peng, Barbara Ma, Shu Hsia Chen, Chien Fu Hung, T. C. Wu
https://health.usnews.com/doctors/barbara-ma-1037870
HPV pseudovirions as DNA delivery vehicles. Ma B Roden RB Hung CF Wu TC; Development of a DNA vaccine targeting Merkel cell polyomavirus. Zeng Q Gomez BP …
https://jcm.asm.org/content/40/3/926
Mar 01, 2002 · The goal of this study was to develop a human papillomavirus (HPV) neutralization assay using HPV pseudovirions generated in vitro. For this purpose, gene transfer efficiency of HPV virus-like particles (VLPs) was improved by using direct interaction between a reporter plasmid and the VLPs. Electron microscopic observation of the interaction between DNA molecules and VLPs revealed that …Author: Latifa Bousarghin, Alba-Lucia Combita-Rojas, Antoine Touzé, Slimane El Mehdaoui, Pierre-Yves Sizaret...
http://europepmc.org/articles/PMC4745065
Feb 01, 2016 · Peng S. et al. Efficient delivery of DNA vaccines using human papillomavirus pseudovirions. Gene Ther 17, 1453–1464 (2010). [PMC free article] Peng S., Ma B., Chen S. H., Hung C. F. & Wu T. DNA vaccines delivered by human papillomavirus pseudovirions as a promising approach for generating antigen-specific CD8+ T cell immunity.Author: Renate L Lamprecht, Paul Kennedy, Suzanne M Huddy, Susanne Bethke, Megan Hendrikse, Inga I Hitzeroth...
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