We have collected information about History Of Rectal Drug Delivery for you. Follow the links to find out details on History Of Rectal Drug Delivery.
https://www.pharmaceutical-journal.com/news-and-analysis/features/exploring-the-unconventional-routes-rectal-and-vaginal-dosage-formulations/11105745.fullarticle?firstPass=false
However, drug delivery via the rectal cavity can be challenged by erratic drug absorption due to potential expulsion of the dosage form and low adhesion to the rectal membrane. In addition, drug bioavailability is affected by the site of drug absorption within the rectal cavity. The superior rectal veins go via the liver whereas the inferior ...
http://globalresearchonline.net/journalcontents/v21-1/13.pdf
The rate and extent of rectal drug absorption are often lower than with oral absorption possibly an inherent factor owing to the relatively small surface area available for drug uptake. Keywords: Rectal Drug Delivery, Rectal Absorption, Suppositories.File Size: 359KB
https://www.slideshare.net/KamleshWadile/rectal-drug-delivery-system
Mar 15, 2016 · • History: In the 18th century, a French pharmacist, Baume used rectal route for administration of suppositories. • Definition: “Rectal drug delivery system means administration of drug or pharmaceutical preparations via rectum for local or systemic effect.” example: suppositories, rectum capsules, enemas, etc. • Rectal products may ...
https://www.pharmatutor.org/articles/discussion-novel-rectal-drug-delivery-systems-recent-review
Rectal drug delivery systems used to deliver the drug by using mucoadhesive polymers is through the mucous membrane of the rectum. Rectal drug delivery is so essential when the oral medication is not possible, Intra venous(I.V) access is not possible and the patients have difficulty in swallowing, nausea and vomiting and for infants or children.
http://www.authorstream.com/Presentation/AJ07-983761-rectal-drug-delivery-system/
Apr 27, 2011 · REASEARCH ARTICLE (cont.) : o smotically-powered rectal drug delivery system An osmotically-powered rectal drug delivery system, was used for the rectal infusion of the model drug antipyrine. The system, which is slightly larger than a normal suppository, has a nominal pumping rate of 43 μl h − 1 over at least 30 h.
https://clinicalgate.com/rectal-and-vaginal-drug-delivery/
• Rectal and vaginal routes are used for local as well as systemic drug delivery and offer some unique advantages. • Both routes have a use in systemic drug delivery when the oral route is not available. • These routes are relatively less popular because of their anogenital nature and privacy aspects. • Local anti-infective drugs, hormones, lubricants, analgesics, anti-inflammatory ...
https://www.slideshare.net/chiranjibi68/rectal-drug-delivery-systems
Jun 22, 2016 · CONCLUSION Rectal administration is truly explored as a potential drug delivery system particularly for drugs that are either too irritating for the gut or undergo extensive first pass metabolism. The rectal drug delivery system offer patients an option that is less invasive and the drug can be administered in unconscious and pediatric patients ...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142099/
Sep 28, 2014 · The contribution of the JCR to the drug delivery field can be best understood by examining the history of controlled drug delivery technologies. Table 1 describes the three generations of drug delivery. The first controlled release formulation was introduced by Smith Kline & French in 1952 for 12-hour delivery of dextroamphetamine (Dexedrine) [2, 3Author: Kinam Park
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123880/
Aug 21, 2017 · Despite the long history of suppository use for both vaginal and rectal drug delivery, the development of suppositories for antiviral drug delivery is in its infancy. Numerous studies, particularly in the development of anti-HIV drugs, demonstrate the potential for both vaginal and rectal drug delivery to prevent and treat HIV infections [ 58 ].Author: Anthony S Ham, Robert W Buckheit
Searching for History Of Rectal Drug Delivery?
You can just click the links above. The data is collected for you.
