High Viscosity Drug Delivery

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Critical Considerations For High ViscosityHigh Volume Drug ...

    https://www.meddeviceonline.com/doc/critical-considerations-for-high-viscosity-high-volume-drug-delivery-devices-0001
    In particular are issues of high viscosity and/or high volume (HV/HV) associated with biologics. Since biologics cannot be taken orally, as the conditions within the stomach denature the molecules, biologics must therefore be delivered via an injection.Location: 1201 Hanley Road Hudson, WI 54016 US

INJECTING HIGH VOLUME, HIGH VISCOSITY DRUGS - …

    https://www.ondrugdelivery.com/injecting-high-volume-high-viscosity-drugs/
    For higher viscosity drug preparations, SHL’s Bertha ® (Figure 1) provides the safe and reliable delivery of up to 60 centipoise. Bertha ® is a disposable, fixed-dose autoinjector that is compatible with either a 1.0 mL or 2.25 mL prefilled syringe.

PATIENT TOLERABILITY WITH HIGH-VISCOSITY, LARGE-VOLUME ...

    https://www.ondrugdelivery.com/patient-tolerability-with-high-viscosity-large-volume-subcutaneous-infusions/
    Characteristics of the drug that impact patient tolerability of high-viscosity, large-volume SC infusion must be considered. Volume and Viscosity. Typically, pharmaceutical companies have had the mindset to pursue high-concentration (high-viscosity) and low-volume formulations based on limitations with previously available delivery systems.

Enable Injections High Volume Wearable Drug Delivery Devices

    https://enableinjections.com/
    Enable Injections develops on-body delivery devices that allow your patients to self-administer high volume (up to 50 ml) and/or high viscosity therapeutics.

Handheld Devices for Injecting High Viscosity Drugs ...

    https://www.greystoneassociates.org/drug-delivery/injectable-drug-delivery/handheld-devices-for-injecting-high-viscosity-drugs/
    Home / Drug Delivery / Injectable Drug Delivery / Handheld Devices for Injecting High Viscosity Drugs Handheld Devices for Injecting High Viscosity Drugs Handheld Devices for Injecting High Viscosity Drugs • September 2018 • No. HVJ525K • US $3,850

Delivery Considerations of Highly Viscous Polymeric Fluids ...

    https://link.springer.com/article/10.1208%2Fs12249-018-0963-x
    Feb 20, 2018 · The high viscosity of the formulation affects both syringeability and formulation performance during injection, necessitating more force with an acceptable needle gauge and time needed. Presently, intravenous, intramuscular, and more convenient subcutaneous route is the most frequently used methods of delivering biologicals.Author: Qiangnan Zhang, Mona A. Fassihi, Reza Fassihi

Needle-free: solving challenges with viscous biologic self ...

    https://biopharmadealmakers.nature.com/users/13785-portal-instruments/posts/17597-needle-free-solving-challenges-with-viscous-biologic-self-injections
    Jun 06, 2017 · However, challenges exist with the delivery of biologics: to be effective, these biologics often need to be delivered at high doses, but regulatory bodies impose limits on …Author: Portal Instruments

Injecting Highly Viscous Drugs Pharmaceutical Technology

    http://www.pharmtech.com/injecting-highly-viscous-drugs
    Nov 02, 2014 · The high mg per mL concentrations of these macromolecule drugs result in high enough viscosities of the injectable product to cause problems for device designers, manufacturers, primary container suppliers, and patients.

Evaluation of the impact of viscosity, injection volume ...

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4646585/
    Nov 11, 2015 · Specifically, less pain was associated with high viscosity (VAS =12.6 mm) than medium (VAS =16.6 mm) or low (VAS =22.1 mm) viscosities, with a significant difference between high and low viscosities (P=0.0002).Author: Cecile Berteau, Orchidée Filipe-Santos, Tao Wang, Humberto E Rojas, Corinne Granger, Florence Schwar...

Home - Weibel CDS

    https://weibelcds.com/
    High Volume, High Viscosity, Modular Wearable Injector and Pump Technology. ... The vision of Large Volume Wearable Drug Delivery becomes reality with the Weibel CDS Wearable Injector Platform. safer, easier and faster drug delivery - tested and fit for purpose ... Weibel CDS AG Mühlenstrasse 26 CH-8200 Schaffhausen +41 71 351 73 21

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