We have collected information about Gram-Positive Commensal Bacteria For Mucosal Vaccine Delivery for you. Follow the links to find out details on Gram-Positive Commensal Bacteria For Mucosal Vaccine Delivery.
https://www.sciencedirect.com/science/article/pii/S0958166996800796
659 Gram-positive commensal bacteria for mucosal vaccine delivery Vincent A Fischetti*, Donata Medaglinit and Gianni Pozzi$ To avoid the use of engineered pathogens for vaccine delivery, systems have been developed that allow the expression of heterologous antigens in …Author: Vincent A Fischetti, Donata Medaglini, Gianni Pozzi
https://www.ncbi.nlm.nih.gov/pubmed/8939641
To avoid the use of engineered pathogens for vaccine delivery, systems have been developed that allow the expression of heterologous antigens in commensal Gram-positive bacteria. In some cases, both a serum IgG and secretory IgA response are induced to the recombinant protein after vaccination, verifying the validity of the approach.Author: Vincent A Fischetti, Donata Medaglini, Gianni Pozzi
https://www.sciencedirect.com/science/article/abs/pii/S0958166996800796
Gram-positive commensal bacteria for mucosal vaccine delivery. Author links open overlay panel Vincent A Fischetti a Donata Medaglini b Gianni Pozzi bAuthor: Vincent A Fischetti, Donata Medaglini, Gianni Pozzi
https://www.sciencedirect.com/science/article/pii/095816699390084A
Non-pathogenic Gram-positive oral commensal bacteria expressing recombinant fusion proteins on their cell surface have been successfully used to raise both a mucosal and a systemic immune response to foreign antigens while colonizing the oropharynx.Author: Vincent A. Fischetti, Donata Medaglini, Marco Oggioni, Gianni Pozzi
https://www.sciencedirect.com/science/article/pii/S0264410X97000261
The idea behind this approach is that non-pathogenic bacteria, capable of colonizing mucosal surfaces, may be used as a delivery system for vaccines aimed at stimulating mucosal immunity. We have developed a genetic system that allows expression of heterologous antigens on the surface of Streptococcus gordonii, a Gram-positive bacterium which is a component of the normal microbial …Author: Donata Medaglini, Catherine M. Rush, Piersante Sestini, Gianni Pozzi
https://www.sciencedirect.com/science/article/pii/S0169409X05000505
Antigen delivery directly to mucosal sites via non-pathogenic commensal bacterial vectors could provide a significant advantage over some of the more traditional vaccines in that live bacteria are capable of stimulating sustained systemic as well as local immune responses . In addition, commensal bacteria are able to colonize the niche invaded ...Author: Rebecca L. Wilson, Dennis E. Hruby
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC41431/
Jul 18, 1995 · A systemic IgG response to Ag5.2 was also induced after oral colonization. Thus, recombinant Gram-positive commensal bacteria may be a safe and effective way of inducing a local and systemic immune response.Author: Donata Medaglini, Gianni Pozzi, T. P. King, V. A. Fischetti
https://onlinelibrary.wiley.com/doi/pdf/10.1111/cei.13301
Keywords: antibodies, gut bacteria, humoral immunity, mucosal vaccine, non-human primates, outer membrane vesicles, plague Introduction Plague is caused by the Gram-negative bacterium, Yersinia pestis. It is an ancient disease, accounting for many deaths over hundreds of years, and still exists in parts of the world today. To protect against infec-Author: A. L. Carvalho, A. Miquel‐Clopés, U. Wegmann, E. Jones, R. Stentz, A. Telatin, N. J. Walker, W. A. B...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3726476/
Jul 23, 2013 · In principle, two types of bacterial vectors can be used to deliver compounds at the mucosal level: attenuated pathogens and non-pathogenic bacteria. Gram-positive commensal or food-grade bacteria constitute attractive good alternatives to pathogenic bacteria [79,81]. Particularly, the food-grade LAB are attractive candidates because they have been used for centuries in the …Author: Rebeca Martín, Rebeca Martín, Sylvie Miquel, Sylvie Miquel, Jonathan Ulmer, Jonathan Ulmer, Noura Ke...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323283/
Lactic acid bacteria (LAB) such as Lactococcus lactis and some strains of Lactobacillus are attractive candidates for the delivery of heterologous antigens, not least due to their GRAS (Generally Regarded As Safe) status, as well as their ability to stimulate mucosal and systemic immune responses against recombinant epitopes associated with them (Wells and Mercenier, 2008).Author: Adilson José da Silva, Teresa Cristina Zangirolami, Maria Teresa Marques Novo-Mansur, Roberto de Cam...
Searching for Gram-Positive Commensal Bacteria For Mucosal Vaccine Delivery?
You can just click the links above. The data is collected for you.
