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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2527668/
Metallic colloidal gold nanoparticles are widely used, can be synthesized in different forms (rods, dots), are commercially available in various size ranges and can be detected at low concentrations. Cells can take up gold nanoparticles without cytotoxic effects (Connor et al 2005; Shenoy et al 2006).Author: Wim H De Jong, Paul Ja Borm
https://www.cell.com/molecular-therapy-family/molecular-therapy/fulltext/S1525-0016(16)30696-7
Jun 01, 2014 · Gold nanoparticles provide an attractive and applicable scaffold for delivery of nucleic acids. In this review, we focus on the use of covalent and noncovalent gold nanoparticle conjugates for applications in gene delivery and RNA-interference technologies.Author: Ya Ding, Ya Ding, Ziwen Jiang, Krishnendu Saha, Chang Soo Kim, Sung Tae Kim, Ryan F Landis, Vincent ...
https://www.nature.com/articles/s41598-018-21331-y
Feb 13, 2018 · Colloidal gold nanoparticles (AuNPs) are of interest as non-toxic carriers for drug delivery owing to their advanced properties, such as extensive …Author: Muhammad U. Farooq, Valentyn Novosad, Valentyn Novosad, Elena A. Rozhkova, Hussain Wali, Asghar Ali,...
https://www.sciencedirect.com/science/article/pii/B9780323328890000145
The long-term circulation coupled with renal clearance from the body provides a practical advantage to the use of gold nanoparticles in drug delivery. Gold nanoparticles are excellent carrier molecules for cancer drug delivery. They can be synthesized in wide range of size with diverse surface functionalities.Author: Parvathy R. Chandran, Reny Thankam Thomas
https://link.springer.com/article/10.1007/s12274-020-2707-y
Mar 06, 2020 · Gold nanoparticles (AuNPs) assembled with fluorescent peptides through Au-S bonds (pep-AuNPs) have been widely used in biomolecular detection. However, due to the endo/lysosomal trapping after the nanoprobes enter cells, the direct delivery of AuNP probes into the cytoplasm for real-time imaging remains a difficult barrier for many cytoplasm-targeting agents. Here, we prepare …Author: Qiang Li, Fengchao Wang, Jie Yang, Dingbin Liu
https://www.sciencedirect.com/science/article/pii/S0169409X08000999
Gold nanoparticles have emerged as a promising scaffold for drug and gene delivery that provide a useful complement to more traditional delivery vehicles. Their combination of low inherent toxicity, high surface area and tunable stability provides them with unique attributes that should enable new delivery …Author: Partha Ghosh, Gang Han, Mrinmoy De, Chae Kyu Kim, Vincent M. Rotello
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501014/
In the present study, we tested gold nanoparticles (AuNPs) for the treatment of HIV. Gold nanoparticles have already been used in gene and cancer targeting, imaging and delivery of therapeutics , reaching clinical trials for cancer patients . Several characteristics make AuNPs highly attractive for clinical use, such as their small size that ...Author: Carolina Garrido, Carrie A Simpson, Noelle P Dahl, Jamee Bresee, Daniel C Whitehead, Erick A Lindsey...
https://pubs.acs.org/doi/10.1021/ja908117a
Over the past decade, gold nanoparticles have been developed that demonstrate a wide variety of applications, including catalysis, (10) bioanalysis, and imaging. (11, 12) Gold nanoparticles are also an ideal drug-delivery scaffold because they are known to be nontoxic and nonimmunogenic.Author: Sarah D. Brown, Paola Nativo, Jo-Ann Smith, David Stirling, Paul R. Edwards, Balaji Venugopal, David...
https://www.sigmaaldrich.com/technical-documents/articles/materials-science/nanomaterials/gold-nanoparticles.html
Introduction. Colloidal gold nanoparticles have been utilized for centuries by artists due to the vibrant colors produced by their interaction with visible light. More recently, these unique optoelectronic properties have been researched and utilized in high technology applications such as organic photovoltaics, sensory probes, therapeutic agents, drug delivery in biological and medical ...
https://www.researchgate.net/publication/286931813_Gold_NanoparticlesA_Boon_to_Drug_Delivery_System
Of these, gold nanoparticles with their unique chemical and physical properties have emerge as promising carrier for delivery of various molecules with therapeutic properties.This review will...
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