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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6843995/
Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) belong to an important therapeutic class for treatment of type 2 diabetes. Six GLP-1 RAs, each utilizing a unique drug delivery strategy, are now approved by the Food and Drug Administration (FDA) and additional, novel GLP-1 RAs are still under development, making for a crowded marketplace and fierce competition among the manufacturers of ...Author: Minzhi Yu, Mason M. Benjamin, Santhanakrishnan Srinivasan, Emily E. Morin, Ekaterina I. Shishatskaya...
https://www.researchgate.net/publication/326447155_Battle_of_GLP-1_delivery_technologies
Six GLP-1 RAs, each utilizing a unique drug delivery strategy, are now approved by the Food and Drug Administration (FDA) and additional, novel GLP-1 RAs are still under development, making for a ...
https://www.ncbi.nlm.nih.gov/pubmed/30009885
Six GLP-1 RAs, each utilizing a unique drug delivery strategy, are now approved by the Food and Drug Administration (FDA) and additional, novel GLP-1 RAs are still under development, making for a crowded marketplace and fierce competition among the manufacturers of these products.Author: Minzhi Yu, Mason M. Benjamin, Santhanakrishnan Srinivasan, Emily E. Morin, Ekaterina I. Shishatskaya...
https://www.mesoscale.com/en/references/2013/beneficial_effects1/
Beneficial effects of parenteral GLP-1 delivery by cell therapy in insulin-deficient streptozotocin diabetic mice. Vasu S, Moffett RC, McCluskey JT, Hamid MH, Irwin N, Flatt PR.
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0162733
Glucagon-like peptide-1 (GLP-1) is an incretin hormone produced by intestinal cells and stimulates insulin secretion from the pancreas in a glucose-dependent manner. Exogenously supplied GLP-1 analogues are used in the treatment of type 2 diabetes. An anti-diabetic effect of Lactobacillus in lowering plasma glucose levels and its use as a vehicle for delivery of protein and antibody fragments ...Author: Yin Lin, Kasper Krogh-Andersen, Julien Pelletier, Harold Marcotte, Claes-Göran Östenson, Lennart Ham...
https://www.hindawi.com/journals/isrn/2012/340632/
Although exendin-4 has longer half-life than GLP-1, it still requires frequent injections to maintain efficacy for the treatment of diabetes. In recent decades, various polymeric delivery systems have been developed for the delivery of GLP-1 and exendin-4 genes or peptides for their long-term action and the extra production in ectopic tissues.Author: Pyung-Hwan Kim, Sung Wan Kim
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