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https://www.sciencedirect.com/science/article/pii/S1359644618304021
In this review, we discuss the potential role of modified cell technologies in ocular drug delivery. Cell engineering technologies for drug delivery Genetically engineered cells. Genetic engineering of the cells is a widely used technique in molecular and cell biology. Cells can be engineered using gene transfer and gene-editing techniques.Author: Tatiana Tennikova, Arto Urtti, Arto Urtti, Arto Urtti
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3970941/
Recombinant protein fusion technology is one of the major advantages in genetically engineered nanocarrier delivery and has been widely used in many applications.31,42,43 Compared with chemically synthesized carriers that require complicated and low-efficiency chemical conjugation reactions with many byproducts, genetically engineered nanocarriers utilize fast and efficient molecular cloning technique to link the drug …Author: Pu Shi, Joshua A Gustafson, J Andrew MacKay
https://www.nature.com/articles/ncomms9791
Nov 10, 2015 · Genetically engineered diatom biosilica (green) containing liposome-encapsulated drug molecules (yellow) can be targeted to both adherent neuroblastoma cells (red) and lymphocyte cells in suspension (purple) by functionalizing the biosilica surface with cell-specific antibodies.Author: Bahman Delalat, Vonda C Sheppard, Soraya Rasi Ghaemi, Shasha Rao, Clive Allan Prestidge, Gordon McPh...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3770064/
With glaucoma currently classified as a neurodegenerative disorder, Neurotech's (NT-501) a nonbiodegradable implant has recently gained consideration for the delivery of protein therapeutics for up to a year to preserve vision cells. The implant encapsulates genetically engineered human retinal pigment epithelium (RPE) cells that secrete CNTF.Author: Dharani Manickavasagam, Moses O. Oyewumi
https://www.sciencedirect.com/science/article/pii/S0928098703001647
Medical applications of genetically engineered polymers are on the horizon, including: depots for drug delivery, hydrogels for pulsatile drug delivery, improved targeted delivery, two stage drug delivery systems, sutures, wound coatings, artificial tendons, tissue engineering, dermal augmentation products for cosmetic and reconstructive surgery, surgical adhesives and sealants for repair of spinal discs, …Author: Jindřich Kopeček
https://www.nature.com/articles/s41551-020-0538-5
Mar 30, 2020 · A retrievable, porous and anti-fibrotic macrodevice for the encapsulation of cells provides long-term protection to human cells expressing therapeutic proteins after device implantation in the ...
http://www.authorstream.com/Presentation/pavan22raju-1931893-implants-drug-delivery-systems/
Sep 15, 2013 · Implants are one of the Advances in drug delivery systems. Implantable drug delivery systems are designed to transmit drugs and fluids into the bloodstream without the repeated insertion of needles. Implantable drug delivery systems are placed completely under the skin usually in a convenient but inconspicuous location.
https://www.aao.org/eyenet/article/promise-of-implantable-drug-delivery-systems
Requiring conjunctival dissection, it is implanted through a 25-gauge needle and self-anchors in the sclera, delivering the drug for up to two years. The implant’s helical coil increases the surface area for drug delivery and uses a polymer coating that’s commonly used for cardiac stents.
http://parts.igem.org/Collections/Drug_Delivery_Projects
iGEM 2013 Drug Delivery Projects . One of the tasks which microorganisms can do well is produce medically useful molecules. One of the first examples of such a case is using genetically engineered E. coli to produce insulin (called "Humulin") for diabetics. The company Genentech was founded to commercialize this venture and still exists today as a wholly owned subsidiary of Roche.
https://www.cell.com/trends/biotechnology/fulltext/S0167-7799(13)00199-6
Dec 01, 2013 · Among the available options, drug delivery from genetically engineered cells anchored on the cochlear implant electrode is the latest and most appealing techniqueAuthor: Fei Tan, Fei Tan, Peter Walshe, Laura Viani, Mohamed Al-Rubeai
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