Gene Delivery System Liposomes

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Liposomes for Use in Gene Delivery - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3066571/
    Dec 15, 2010 · Most liposomal formulations used for gene delivery consist of a combination of charged lipids and neutral helper lipids [12, 22–24, 26, 28]. The neutral helper lipids used are often dioleoylphosphatidylethanolamine (DOPE), which is the most widely used neutral helper lipid, or dioleoylphosphatidylcholine (DOPC).Author: Daniel A. Balazs, Wt. Godbey

Liposomal Gene Delivery System - an overview ...

    https://www.sciencedirect.com/topics/neuroscience/liposomal-gene-delivery-system
    In contrast, liposomal gene transfer has been established as a promising therapeutic modality for brain tumors. 3 Good transfer efficiency, safety, simple design, and their unique capability to carry, not only genetic material, but also proteins, chemicals, or physical particles into a cell make these artificial lipid bilayered vesicles useful and exciting therapeutic tools. However, viral-based vectors and therapeutic …

Liposomes in Gene Delivery - CRC Press Book

    https://www.crcpress.com/Liposomes-in-Gene-Delivery/Lasic/p/book/9780849331091
    Liposomes in Gene Delivery covers both-molecular biologists will gain a basic knowledge of lipids, liposomes, and other gene delivery vehicles; lipid and drug delivery scientists will better understand DNA, molecular biology, and DNA manipulation.

(PDF) Liposomes as a gene delivery system - ResearchGate

    https://www.researchgate.net/publication/12950633_Liposomes_as_a_gene_delivery_system
    The key to success for any gene therapy strategy is to design a vector able to serve as a safe and efficient gene delivery vehicle. This has encouraged the development of nonviral DNA-mediated gene transfer techniques such as liposomes. Many liposome-based DNA delivery systems …

Liposomes as a gene delivery system - SciELO

    http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000200004
    One important goal for gene therapy is to develop a delivery system that can be injected into the bloodstream and deliver the DNA sequence to the appropriate tissue. The use of conventional liposomes for gene therapy implies a preferential localization in the liver, spleen and lung.

Liposomal gene delivery system - LinkedIn SlideShare

    https://www.slideshare.net/DurgaBhavani60/liposomal-gene-delivery-system
    Jul 14, 2019 · LIPOSOMAL GENE DELIVERY SYSTEMS: INTRODUCTION: Liposomes have been explored as a delivery system for DNA as early as in 1979. The encapsulation of plasmid DNA into liposomes and the introduction of poliovirus RNA and SV40 DNA into cells via liposomes were reported between 1979 and 1980. These are vesicles that can easily merge with the cell membrane. since, …

Liposomal Drug Delivery - an overview ScienceDirect Topics

    https://www.sciencedirect.com/topics/pharmacology-toxicology-and-pharmaceutical-science/liposomal-drug-delivery
    Liposomes, micelles, and polymer–drug conjugates are the widely explored nano drug delivery systems. The development of polymeric liposomes as drug delivery systems dates back to the 1970s [79–81]. The first FDA-approved (1995) nanopharmaceutical, Doxil [82], is based on liposomal drug delivery technology.

Delivery systems for gene therapy - PubMed Central (PMC)

    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3722627/
    The genetic material can be placed in liposomes in order to increase the DNA uptake in tissue culture. The last of these vectors uses a process by which the micro projectiles (e.g., gold or tungsten) are coated with DNA and then accelerated by either helium pressure or a high-voltage electrical discharge, thus,...

Liposomes for Use in Gene Delivery - Hindawi

    https://www.hindawi.com/journals/jdd/2011/326497/
    Most liposomal formulations used for gene delivery consist of a combination of charged lipids and neutral helper lipids [12, 22–24, 26, 28]. The neutral helper lipids used are often dioleoylphosphatidylethanolamine (DOPE), which is the most widely used neutral helper lipid, or dioleoylphosphatidylcholine (DOPC).Author: Daniel A. Balazs, Wt. Godbey

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