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https://www.sciencedirect.com/science/article/pii/S0169409X05001936
2. Dendrimers. Since their conception in the late 1970s and early 1980s the unique properties of dendrimers have spawned a whole range of new research areas ranging from drug and gene delivery applications to processing, diagnostics, and nanoengineering .. In comparison to the traditional polymers that initiated a materials revolution in the second half of the last century, dendrimers are ...Author: Christine Dufès, Ijeoma F. Uchegbu, Andreas G. Schätzlein
https://www.sciencedirect.com/science/article/pii/S2352940718301641
PAMAM dendrimers are able to create stable PAMAM-nucleic acid complexes to prevent nucleases activities. These properties have been considered by the researchers to design nanocarriers based on PAMAM dendrimers for gene delivery purposes , , , , , , . From the biophysical studies concerning PAMAM/DNA complexes, electrostatic interactions are ...Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6269116/
PAMAM dendrimers are able to create stable PAMAM-nucleic acid complexes to prevent nucleases activities. These properties have been considered by the researchers to design nanocarriers based on PAMAM dendrimers for gene delivery purposes [81–85,90,91]. From the biophysical studies concerning PAMAM/DNA complexes, electrostatic interactions are ...Author: Fereydoon Abedi-Gaballu, Fereydoon Abedi-Gaballu, Gholamreza Dehghan, Maryam Ghaffari, Maryam Ghaffa...
https://pubs.acs.org/doi/10.1021/cr500542t
May 06, 2015 · A Self-Assembled Coumarin-Anchored Dendrimer for Efficient Gene Delivery and Light-Responsive Drug Delivery. Biomacromolecules 2018, 19 (6) , 2194-2201. DOI: 10.1021/acs.biomac.8b00246. Gancheng Zuo, Aming Xie, Xihao Pan, Ting Su, Junjian Li, Wei Dong. Fluorine-Doped Cationic Carbon Dots for Efficient Gene Delivery.Author: Jiepin Yang, Qiang Zhang, Hong Chang, Yiyun Cheng
https://onlinelibrary.wiley.com/doi/full/10.1111/jphp.12104
Jul 19, 2013 · Dendrimers for non‐viral gene delivery. Various viral and non‐viral gene delivery systems have been developed for the delivery of genetic materials to different organs, tissues and cells. While viral vectors are the most capable vehicles, their limitations include their high carcinogenicity and immunogenicity in vivo.Author: Sahil P. Chaplot, Ilva D. Rupenthal
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3471158/
Non-viral vectors can be designed in a very biocompatible and non-toxic form with enhancement in physicochemical properties for gene therapy. In this article, we have discussed a variety of modification techniques and cell-targeting strategies to improve chitosan and PAMAM dendrimers for gene delivery.Author: Qingxing Xu, Chi-Hwa Wang, Daniel Wayne Pack
https://pubs.acs.org/doi/10.1021/bc9600630
Transfection of cultured cells has been reported using complexes between DNA and spherical cationic polyamidoamine polymers (Starburst dendrimers) that consist of primary amines on the surface and tertiary amines in the interior. The transfection activity of the dendrimers is dramatically enhanced (>50-fold) by heat treatment in a variety of solvolytic solvents, e.g., water or butanol. Such ...Author: Mary X. Tang, Carl T. Redemann, Francis C. Szoka
https://www.sigmaaldrich.com/materials-science/material-science-products.html?TablePage=16375655
Applications of dendrimers Applications highlighted in recent literature include drug delivery, gene transfection, catalysis, energy harvesting, photo activity, molecular weight and size determination, rheology modification, and nanoscale science and technology. 1, 2 Dendrimer synthesis
https://link.springer.com/chapter/10.1007/978-3-7091-1206-9_14
Nov 05, 2012 · Delivery of nucleic acids to target cells can be achieved by both viral and nonviral delivery systems. Both of these methods have distinct advantages …Author: Jaroslav Šebestík, Milan Reiniš, Jan Ježek
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